Myostatin regulates fatty acid desaturation and fat deposition through MEF2C/miR222/SCD5 cascade in pigs

Myostatin (MSTN), associated with the “double muscling” phenotype, affects muscle growth and fat deposition in animals, whereas how MSTN affects adipogenesis remains to be discovered. Here we show that MSTN can act through the MEF2C/miR222/SCD5 cascade to regulate fatty acid metabolism. We generated...

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Detalles Bibliográficos
Autores principales: Ren, Hongyan, Xiao, Wei, Qin, Xingliang, Cai, Gangzhi, Chen, Hao, Hua, Zaidong, Cheng, Cheng, Li, Xinglei, Hua, Wenjun, Xiao, Hongwei, Zhang, Liping, Dai, Jiali, Zheng, Xinmin, Zhu, Zhe, Qian, Chong, Yao, Jie, Bi, Yanzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584575/
https://www.ncbi.nlm.nih.gov/pubmed/33097765
http://dx.doi.org/10.1038/s42003-020-01348-8

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