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Exogenous L-arginine increases intestinal stem cell function through CD90+ stromal cells producing mTORC1-induced Wnt2b

The renewal and repair of intestinal epithelium depend on the self-renewal of intestinal stem cells (ISCs) under physiological and pathological conditions. Although previous work has established that exogenous nutrients regulate adult stem cell activity, little is known about the regulatory effect o...

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Detalles Bibliográficos
Autores principales: Hou, Qihang, Dong, Yuanyang, Huang, Jingxi, Liao, Chaoyong, Lei, Jiaqi, Wang, Youli, Lai, Yujiao, Bian, Yifei, He, Yang, Sun, Jingjing, Sun, Meng, Jiang, Qiuyu, Wang, Bo, Yu, Zhengquan, Guo, Yuming, Zhang, Bingkun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584578/
https://www.ncbi.nlm.nih.gov/pubmed/33097830
http://dx.doi.org/10.1038/s42003-020-01347-9