Combination of syringaresinol–di–O–β-d-glucoside and chlorogenic acid shows behavioral pharmacological anxiolytic activity and activation of hippocampal BDNF–TrkB signaling

Mental stress, such as anxiety and conflict, causes physiological changes such as dysregulation of autonomic nervous activity, depression, and gastric ulcers. It also induces glucocorticoid production and changes in hippocampal brain-derived neurotrophic factor (BDNF) levels. We previously reported...

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Detalles Bibliográficos
Autores principales: Miyazaki, Shouhei, Fujita, Yoshio, Oikawa, Hirotaka, Takekoshi, Hideo, Soya, Hideaki, Ogata, Masato, Fujikawa, Takahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584579/
https://www.ncbi.nlm.nih.gov/pubmed/33097741
http://dx.doi.org/10.1038/s41598-020-74866-4

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