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The miR-30a-5p/CLCF1 axis regulates sorafenib resistance and aerobic glycolysis in hepatocellular carcinoma

HCC (hepatocellular carcinoma) is a major health threat for the Chinese population and has poor prognosis because of strong resistance to chemotherapy in patients. For instance, a considerable challenge for the treatment of HCC is sorafenib resistance. The aberrant glucose metabolism in cancer cells...

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Detalles Bibliográficos
Autores principales: Zhang, Zhongqiang, Tan, Xiao, Luo, Jing, Yao, Hongliang, Si, Zhongzhou, Tong, Jing-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584607/
https://www.ncbi.nlm.nih.gov/pubmed/33097691
http://dx.doi.org/10.1038/s41419-020-03123-3