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FGFR3(△7–9) promotes tumor progression via the phosphorylation and destabilization of ten-eleven translocation-2 in human hepatocellular carcinoma
Overexpression of fibroblast growth factor receptor 3 (FGFR3) correlates with more severe clinical features of hepatocellular carcinoma (HCC). Our previous study has shown that FGFR3(∆7–9), a novel splicing mutation of FGFR3, contributes significantly to HCC malignant character, but the epigenetic m...
Autores principales: | Jin, Zhijian, Feng, Haoran, Liang, Juyong, Jing, Xiaoqian, Zhao, Qiwu, Zhan, Ling, Shen, Baiyong, Cheng, Xi, Su, Liping, Qiu, Weihua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584635/ https://www.ncbi.nlm.nih.gov/pubmed/33097695 http://dx.doi.org/10.1038/s41419-020-03089-2 |
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