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Development of a novel thymidylate synthase (TS) inhibitor capable of up-regulating P53 expression and inhibiting angiogenesis in NSCLC

INTRODUCTION: The development of a new type of Thymidylate synthase (TS) inhibitor that could inhibit cancer cells' proliferation and anti-angiogenesis is of great significance for cancer's clinical treatment. OBJECTIVES: Our research hopes to develop a TS inhibitor that is more effective...

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Detalles Bibliográficos
Autores principales: Li, Xin-yang, Wang, De-pu, Lu, Guo-qing, Liu, Kai-li, Zhang, Ting-jian, Li, Shuai, Mohamed O, Kamara, Xue, Wen-han, Qian, Xin-hua, Meng, Fan-hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584679/
https://www.ncbi.nlm.nih.gov/pubmed/33133686
http://dx.doi.org/10.1016/j.jare.2020.07.008