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Brusatol suppresses STAT3-driven metastasis by downregulating epithelial-mesenchymal transition in hepatocellular carcinoma

INTRODUCTION: Epithelial-mesenchymal transition (EMT) is a process of transdifferentiation where epithelial cells attain mesenchymal phenotype to gain invasive properties and thus, can contribute to metastasis of tumor cells. OBJECTIVES: The antimetastatic and antitumor efficacy of brusatol (BT) was...

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Detalles Bibliográficos
Autores principales:	Lee, Jong Hyun, Mohan, Chakrabhavi Dhananjaya, Deivasigamani, Amudha, Jung, Young Yun, Rangappa, Shobith, Basappa, Salundi, Chinnathambi, Arunachalam, Alahmadi, Tahani Awad, Alharbi, Sulaiman Ali, Garg, Manoj, Lin, Zhi-Xiu, Rangappa, Kanchugarakoppal S., Sethi, Gautam, Hui, Kam Man, Ahn, Kwang Seok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584682/ https://www.ncbi.nlm.nih.gov/pubmed/33133685 http://dx.doi.org/10.1016/j.jare.2020.07.004

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