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Efficacy and Safety of Ivabradine Once-Daily Prolonged-Release versus Twice-Daily Immediate-Release Formulation in Patients with Stable Chronic Heart Failure with Systolic Dysfunction: A Randomized, Double-Blind, Phase 3 Non-Inferiority (PROFICIENT) Study
INTRODUCTION: Dosing frequency is an important factor influencing medication compliance in patients with heart failure (HF), which in turn is imperative in achieving the desired therapeutic outcome. Here we assessed the efficacy and safety of ivabradine prolonged-release (PR) once-daily (test) vs. i...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Healthcare
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584698/ https://www.ncbi.nlm.nih.gov/pubmed/33006062 http://dx.doi.org/10.1007/s40119-020-00200-8 |