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The Physiologic Basis and Clinical Outcomes of Combined Impella and Veno-Arterial Extracorporeal Membrane Oxygenation Support in Cardiogenic Shock
Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) provides effective hemodynamic support in cardiogenic shock, but in some cases may be complicated by left ventricular (LV) distension and pulmonary edema. The Impella, a catheter-mounted microaxial pump has been used to unload the LV. Recen...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Healthcare
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584716/ https://www.ncbi.nlm.nih.gov/pubmed/32424689 http://dx.doi.org/10.1007/s40119-020-00175-6 |
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author | Lim, Hoong Sern |
author_facet | Lim, Hoong Sern |
author_sort | Lim, Hoong Sern |
collection | PubMed |
description | Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) provides effective hemodynamic support in cardiogenic shock, but in some cases may be complicated by left ventricular (LV) distension and pulmonary edema. The Impella, a catheter-mounted microaxial pump has been used to unload the LV. Recent studies have compared the clinical outcomes of VA-ECMO to the combination of Impella and VA-ECMO. The purpose of this review is threefold: firstly, to discuss the physiological effects of Impella support in addition to VA-ECMO, secondly to review published studies on the outcome of this combined support, and thirdly to provide a practical overview of the approach to combining Impella and VA-ECMO. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s40119-020-00175-6) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-7584716 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer Healthcare |
record_format | MEDLINE/PubMed |
spelling | pubmed-75847162020-10-29 The Physiologic Basis and Clinical Outcomes of Combined Impella and Veno-Arterial Extracorporeal Membrane Oxygenation Support in Cardiogenic Shock Lim, Hoong Sern Cardiol Ther Review Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) provides effective hemodynamic support in cardiogenic shock, but in some cases may be complicated by left ventricular (LV) distension and pulmonary edema. The Impella, a catheter-mounted microaxial pump has been used to unload the LV. Recent studies have compared the clinical outcomes of VA-ECMO to the combination of Impella and VA-ECMO. The purpose of this review is threefold: firstly, to discuss the physiological effects of Impella support in addition to VA-ECMO, secondly to review published studies on the outcome of this combined support, and thirdly to provide a practical overview of the approach to combining Impella and VA-ECMO. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s40119-020-00175-6) contains supplementary material, which is available to authorized users. Springer Healthcare 2020-05-18 2020-12 /pmc/articles/PMC7584716/ /pubmed/32424689 http://dx.doi.org/10.1007/s40119-020-00175-6 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) . |
spellingShingle | Review Lim, Hoong Sern The Physiologic Basis and Clinical Outcomes of Combined Impella and Veno-Arterial Extracorporeal Membrane Oxygenation Support in Cardiogenic Shock |
title | The Physiologic Basis and Clinical Outcomes of Combined Impella and Veno-Arterial Extracorporeal Membrane Oxygenation Support in Cardiogenic Shock |
title_full | The Physiologic Basis and Clinical Outcomes of Combined Impella and Veno-Arterial Extracorporeal Membrane Oxygenation Support in Cardiogenic Shock |
title_fullStr | The Physiologic Basis and Clinical Outcomes of Combined Impella and Veno-Arterial Extracorporeal Membrane Oxygenation Support in Cardiogenic Shock |
title_full_unstemmed | The Physiologic Basis and Clinical Outcomes of Combined Impella and Veno-Arterial Extracorporeal Membrane Oxygenation Support in Cardiogenic Shock |
title_short | The Physiologic Basis and Clinical Outcomes of Combined Impella and Veno-Arterial Extracorporeal Membrane Oxygenation Support in Cardiogenic Shock |
title_sort | physiologic basis and clinical outcomes of combined impella and veno-arterial extracorporeal membrane oxygenation support in cardiogenic shock |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584716/ https://www.ncbi.nlm.nih.gov/pubmed/32424689 http://dx.doi.org/10.1007/s40119-020-00175-6 |
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