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Survival-Inferred Fragility Index of Phase 3 Clinical Trials Evaluating Immune Checkpoint Inhibitors

IMPORTANCE: In science and medical research, extreme and dichotomous conclusions may be drawn based on whether the P value falls above or below the threshold. The fragility index (ie, the minimum number of changes from nonevents to events resulting in loss of statistical significance) captures the v...

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Detalles Bibliográficos
Autores principales: Bomze, David, Asher, Nethanel, Hasan Ali, Omar, Flatz, Lukas, Azoulay, Daniel, Markel, Gal, Meirson, Tomer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584930/
https://www.ncbi.nlm.nih.gov/pubmed/33095247
http://dx.doi.org/10.1001/jamanetworkopen.2020.17675

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