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Measurement Properties of Existing Patient-Reported Outcome Measures on Medication Adherence: Systematic Review

BACKGROUND: Medication adherence is essential for improving the health outcomes of patients. Various patient-reported outcome measures (PROMs) have been developed to measure medication adherence in patients. However, no study has summarized the psychometric properties of these PROMs to guide selecti...

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Autores principales: Kwan, Yu Heng, Weng, Si Dun, Loh, Dionne Hui Fang, Phang, Jie Kie, Oo, Livia Jia Yi, Blalock, Dan V, Chew, Eng Hui, Yap, Kai Zhen, Tan, Corrinne Yong Koon, Yoon, Sungwon, Fong, Warren, Østbye, Truls, Low, Lian Leng, Bosworth, Hayden Barry, Thumboo, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JMIR Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584986/
https://www.ncbi.nlm.nih.gov/pubmed/33034566
http://dx.doi.org/10.2196/19179
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author Kwan, Yu Heng
Weng, Si Dun
Loh, Dionne Hui Fang
Phang, Jie Kie
Oo, Livia Jia Yi
Blalock, Dan V
Chew, Eng Hui
Yap, Kai Zhen
Tan, Corrinne Yong Koon
Yoon, Sungwon
Fong, Warren
Østbye, Truls
Low, Lian Leng
Bosworth, Hayden Barry
Thumboo, Julian
author_facet Kwan, Yu Heng
Weng, Si Dun
Loh, Dionne Hui Fang
Phang, Jie Kie
Oo, Livia Jia Yi
Blalock, Dan V
Chew, Eng Hui
Yap, Kai Zhen
Tan, Corrinne Yong Koon
Yoon, Sungwon
Fong, Warren
Østbye, Truls
Low, Lian Leng
Bosworth, Hayden Barry
Thumboo, Julian
author_sort Kwan, Yu Heng
collection PubMed
description BACKGROUND: Medication adherence is essential for improving the health outcomes of patients. Various patient-reported outcome measures (PROMs) have been developed to measure medication adherence in patients. However, no study has summarized the psychometric properties of these PROMs to guide selection for use in clinical practice or research. OBJECTIVE: This study aims to evaluate the quality of the PROMs used to measure medication adherence. METHODS: This study was guided by the PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analysis) guidelines. Relevant articles were retrieved from the EMBASE, PubMed, Cochrane Library, Web of Science, and CINAHL (Cumulative Index to Nursing and Allied Health Literature) databases. The PROMs were then evaluated based on the COnsensus-based Standards for the selection of health Measurement Instruments (COSMIN) guidelines. RESULTS: A total of 121 unique medication adherence PROMs from 214 studies were identified. Hypotheses testing for construct validity and internal consistency were the most frequently assessed measurement properties. PROMs with at least a moderate level of evidence for ≥5 measurement properties include the Adherence Starts with Knowledge 20, Compliance Questionnaire-Rheumatology, General Medication Adherence Scale, Hill-Bone Scale, Immunosuppressant Therapy Barrier Scale, Medication Adherence Reasons Scale (MAR-Scale) revised, 5-item Medication Adherence Rating Scale (MARS-5), 9-item MARS (MARS-9), 4-item Morisky Medication Adherence Scale (MMAS-4), 8-item MMAS (MMAS-8), Self-efficacy for Appropriate Medication Adherence Scale, Satisfaction with Iron Chelation Therapy, Test of Adherence to Inhalers, and questionnaire by Voils. The MAR-Scale revised, MMAS-4, and MMAS-8 have been administered electronically. CONCLUSIONS: This study identified 121 PROMs for medication adherence and provided synthesized evidence for the measurement properties of these PROMs. The findings from this study may assist clinicians and researchers in selecting suitable PROMs to assess medication adherence.
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spelling pubmed-75849862020-10-28 Measurement Properties of Existing Patient-Reported Outcome Measures on Medication Adherence: Systematic Review Kwan, Yu Heng Weng, Si Dun Loh, Dionne Hui Fang Phang, Jie Kie Oo, Livia Jia Yi Blalock, Dan V Chew, Eng Hui Yap, Kai Zhen Tan, Corrinne Yong Koon Yoon, Sungwon Fong, Warren Østbye, Truls Low, Lian Leng Bosworth, Hayden Barry Thumboo, Julian J Med Internet Res Review BACKGROUND: Medication adherence is essential for improving the health outcomes of patients. Various patient-reported outcome measures (PROMs) have been developed to measure medication adherence in patients. However, no study has summarized the psychometric properties of these PROMs to guide selection for use in clinical practice or research. OBJECTIVE: This study aims to evaluate the quality of the PROMs used to measure medication adherence. METHODS: This study was guided by the PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analysis) guidelines. Relevant articles were retrieved from the EMBASE, PubMed, Cochrane Library, Web of Science, and CINAHL (Cumulative Index to Nursing and Allied Health Literature) databases. The PROMs were then evaluated based on the COnsensus-based Standards for the selection of health Measurement Instruments (COSMIN) guidelines. RESULTS: A total of 121 unique medication adherence PROMs from 214 studies were identified. Hypotheses testing for construct validity and internal consistency were the most frequently assessed measurement properties. PROMs with at least a moderate level of evidence for ≥5 measurement properties include the Adherence Starts with Knowledge 20, Compliance Questionnaire-Rheumatology, General Medication Adherence Scale, Hill-Bone Scale, Immunosuppressant Therapy Barrier Scale, Medication Adherence Reasons Scale (MAR-Scale) revised, 5-item Medication Adherence Rating Scale (MARS-5), 9-item MARS (MARS-9), 4-item Morisky Medication Adherence Scale (MMAS-4), 8-item MMAS (MMAS-8), Self-efficacy for Appropriate Medication Adherence Scale, Satisfaction with Iron Chelation Therapy, Test of Adherence to Inhalers, and questionnaire by Voils. The MAR-Scale revised, MMAS-4, and MMAS-8 have been administered electronically. CONCLUSIONS: This study identified 121 PROMs for medication adherence and provided synthesized evidence for the measurement properties of these PROMs. The findings from this study may assist clinicians and researchers in selecting suitable PROMs to assess medication adherence. JMIR Publications 2020-10-09 /pmc/articles/PMC7584986/ /pubmed/33034566 http://dx.doi.org/10.2196/19179 Text en ©Yu Heng Kwan, Si Dun Weng, Dionne Hui Fang Loh, Jie Kie Phang, Livia Jia Yi Oo, Dan V Blalock, Eng Hui Chew, Kai Zhen Yap, Corrinne Yong Koon Tan, Sungwon Yoon, Warren Fong, Truls Østbye, Lian Leng Low, Hayden Barry Bosworth, Julian Thumboo. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 09.10.2020. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on http://www.jmir.org/, as well as this copyright and license information must be included.
spellingShingle Review
Kwan, Yu Heng
Weng, Si Dun
Loh, Dionne Hui Fang
Phang, Jie Kie
Oo, Livia Jia Yi
Blalock, Dan V
Chew, Eng Hui
Yap, Kai Zhen
Tan, Corrinne Yong Koon
Yoon, Sungwon
Fong, Warren
Østbye, Truls
Low, Lian Leng
Bosworth, Hayden Barry
Thumboo, Julian
Measurement Properties of Existing Patient-Reported Outcome Measures on Medication Adherence: Systematic Review
title Measurement Properties of Existing Patient-Reported Outcome Measures on Medication Adherence: Systematic Review
title_full Measurement Properties of Existing Patient-Reported Outcome Measures on Medication Adherence: Systematic Review
title_fullStr Measurement Properties of Existing Patient-Reported Outcome Measures on Medication Adherence: Systematic Review
title_full_unstemmed Measurement Properties of Existing Patient-Reported Outcome Measures on Medication Adherence: Systematic Review
title_short Measurement Properties of Existing Patient-Reported Outcome Measures on Medication Adherence: Systematic Review
title_sort measurement properties of existing patient-reported outcome measures on medication adherence: systematic review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584986/
https://www.ncbi.nlm.nih.gov/pubmed/33034566
http://dx.doi.org/10.2196/19179
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