Cargando…
The influence of stone size on spontaneous passage of common bile duct stones in patients with acute cholangitis: A retrospective cohort study
BACKGROUND: The common bile duct (CBD) stones passage in patients with cholangitis was unclear. This study aimed to evaluate the effect on CBD stone sizes and predicting factors on spontaneous passage in patients with cholangitis. METHOD: The medical records of cholangitis at Her Royal Highness Prin...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584998/ https://www.ncbi.nlm.nih.gov/pubmed/33133588 http://dx.doi.org/10.1016/j.amsu.2020.10.040 |
_version_ | 1783599699451707392 |
---|---|
author | Sanguanlosit, Sarat Viriyaroj, Vichit Yodying, Hariruk Rookkachart, Thammanij Sathornviriyapong, Suun Boonsinsukh, Thana |
author_facet | Sanguanlosit, Sarat Viriyaroj, Vichit Yodying, Hariruk Rookkachart, Thammanij Sathornviriyapong, Suun Boonsinsukh, Thana |
author_sort | Sanguanlosit, Sarat |
collection | PubMed |
description | BACKGROUND: The common bile duct (CBD) stones passage in patients with cholangitis was unclear. This study aimed to evaluate the effect on CBD stone sizes and predicting factors on spontaneous passage in patients with cholangitis. METHOD: The medical records of cholangitis at Her Royal Highness Princess Maha Chakri Sirindhorn Medical Center, Srinakharinwirot University from January 2014 to December 2019 were retrospectively reviewed. Patients with acute cholangitis from CBD stones underwent ERCP in the same admission were enrolled. RESULT: Of the 96 patients, The rate of spontaneous passage of CBD stones was 19.8%. By univariate analysis, factors significantly associated with a predictor of spontaneous CBD stone passage in patient with cholangitis were single CBD stone (p = 0.001), CBD stone diameter < 5 mm (p < 0.001), and clinical symptom improved before ERCP procedure (p = 0.004). Multivariate logistic regression analyses also revealed that these three factors were significantly associated with spontaneous passage. From ROC curve analysis, stone size of less than 4.85 mm was more likely to pass spontaneously with acceptable sensitivity (81.8%) and specificity (78.9%). CONCLUSIONS: CBD stone diameter < 5 mm, single CBD stone and improved clinical symptom before ERCP procedure are key predictors of spontaneous CBD stone passage in cholangitis. |
format | Online Article Text |
id | pubmed-7584998 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-75849982020-10-30 The influence of stone size on spontaneous passage of common bile duct stones in patients with acute cholangitis: A retrospective cohort study Sanguanlosit, Sarat Viriyaroj, Vichit Yodying, Hariruk Rookkachart, Thammanij Sathornviriyapong, Suun Boonsinsukh, Thana Ann Med Surg (Lond) Cohort Study BACKGROUND: The common bile duct (CBD) stones passage in patients with cholangitis was unclear. This study aimed to evaluate the effect on CBD stone sizes and predicting factors on spontaneous passage in patients with cholangitis. METHOD: The medical records of cholangitis at Her Royal Highness Princess Maha Chakri Sirindhorn Medical Center, Srinakharinwirot University from January 2014 to December 2019 were retrospectively reviewed. Patients with acute cholangitis from CBD stones underwent ERCP in the same admission were enrolled. RESULT: Of the 96 patients, The rate of spontaneous passage of CBD stones was 19.8%. By univariate analysis, factors significantly associated with a predictor of spontaneous CBD stone passage in patient with cholangitis were single CBD stone (p = 0.001), CBD stone diameter < 5 mm (p < 0.001), and clinical symptom improved before ERCP procedure (p = 0.004). Multivariate logistic regression analyses also revealed that these three factors were significantly associated with spontaneous passage. From ROC curve analysis, stone size of less than 4.85 mm was more likely to pass spontaneously with acceptable sensitivity (81.8%) and specificity (78.9%). CONCLUSIONS: CBD stone diameter < 5 mm, single CBD stone and improved clinical symptom before ERCP procedure are key predictors of spontaneous CBD stone passage in cholangitis. Elsevier 2020-10-21 /pmc/articles/PMC7584998/ /pubmed/33133588 http://dx.doi.org/10.1016/j.amsu.2020.10.040 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Cohort Study Sanguanlosit, Sarat Viriyaroj, Vichit Yodying, Hariruk Rookkachart, Thammanij Sathornviriyapong, Suun Boonsinsukh, Thana The influence of stone size on spontaneous passage of common bile duct stones in patients with acute cholangitis: A retrospective cohort study |
title | The influence of stone size on spontaneous passage of common bile duct stones in patients with acute cholangitis: A retrospective cohort study |
title_full | The influence of stone size on spontaneous passage of common bile duct stones in patients with acute cholangitis: A retrospective cohort study |
title_fullStr | The influence of stone size on spontaneous passage of common bile duct stones in patients with acute cholangitis: A retrospective cohort study |
title_full_unstemmed | The influence of stone size on spontaneous passage of common bile duct stones in patients with acute cholangitis: A retrospective cohort study |
title_short | The influence of stone size on spontaneous passage of common bile duct stones in patients with acute cholangitis: A retrospective cohort study |
title_sort | influence of stone size on spontaneous passage of common bile duct stones in patients with acute cholangitis: a retrospective cohort study |
topic | Cohort Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584998/ https://www.ncbi.nlm.nih.gov/pubmed/33133588 http://dx.doi.org/10.1016/j.amsu.2020.10.040 |
work_keys_str_mv | AT sanguanlositsarat theinfluenceofstonesizeonspontaneouspassageofcommonbileductstonesinpatientswithacutecholangitisaretrospectivecohortstudy AT viriyarojvichit theinfluenceofstonesizeonspontaneouspassageofcommonbileductstonesinpatientswithacutecholangitisaretrospectivecohortstudy AT yodyinghariruk theinfluenceofstonesizeonspontaneouspassageofcommonbileductstonesinpatientswithacutecholangitisaretrospectivecohortstudy AT rookkachartthammanij theinfluenceofstonesizeonspontaneouspassageofcommonbileductstonesinpatientswithacutecholangitisaretrospectivecohortstudy AT sathornviriyapongsuun theinfluenceofstonesizeonspontaneouspassageofcommonbileductstonesinpatientswithacutecholangitisaretrospectivecohortstudy AT boonsinsukhthana theinfluenceofstonesizeonspontaneouspassageofcommonbileductstonesinpatientswithacutecholangitisaretrospectivecohortstudy AT sanguanlositsarat influenceofstonesizeonspontaneouspassageofcommonbileductstonesinpatientswithacutecholangitisaretrospectivecohortstudy AT viriyarojvichit influenceofstonesizeonspontaneouspassageofcommonbileductstonesinpatientswithacutecholangitisaretrospectivecohortstudy AT yodyinghariruk influenceofstonesizeonspontaneouspassageofcommonbileductstonesinpatientswithacutecholangitisaretrospectivecohortstudy AT rookkachartthammanij influenceofstonesizeonspontaneouspassageofcommonbileductstonesinpatientswithacutecholangitisaretrospectivecohortstudy AT sathornviriyapongsuun influenceofstonesizeonspontaneouspassageofcommonbileductstonesinpatientswithacutecholangitisaretrospectivecohortstudy AT boonsinsukhthana influenceofstonesizeonspontaneouspassageofcommonbileductstonesinpatientswithacutecholangitisaretrospectivecohortstudy |