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Epigenetic mutation load is weakly correlated with epigenetic age acceleration

DNA methylation (DNAm) age estimators are widely used to study aging-related conditions. It is not yet known whether DNAm age is associated with the accumulation of stochastic epigenetic mutations (SEMs), which reflect dysfunctions of the epigenetic maintenance system. Here, we defined epigenetic mu...

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Detalles Bibliográficos
Autores principales:	Yan, Qi, Paul, Kimberly C., Lu, Ake T., Kusters, Cynthia, Binder, Alexandra M., Horvath, Steve, Ritz, Beate
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585066/ https://www.ncbi.nlm.nih.gov/pubmed/32991324 http://dx.doi.org/10.18632/aging.103950

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