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Prothrombotic effects of high uric acid in mice via activation of MEF2C-dependent NF-κB pathway by upregulating let-7c

Serum uric acid is reportedly associated with thrombosis development. However, still unclear is the mechanism of high uric acid in thrombosis with the involvement of let-7c. In an aim to fill this void, we conducted this study by treating mice and human umbilical vein endothelial cells with high uri...

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Detalles Bibliográficos
Autores principales:	Cheng, Xiaoyu, Liu, Tian, Ma, Lidan, Liu, Zhen, Xin, Ying, Jia, Zhaotong, Chen, Ying, Li, Changgui, Sun, Ruixia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585100/ https://www.ncbi.nlm.nih.gov/pubmed/32960786 http://dx.doi.org/10.18632/aging.103540

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