Cargando…

Identification of Novel Therapeutic Molecular Targets in Inflammatory Bowel Disease by Using Genetic Databases

PURPOSE: Utilization of genetic databases to identify genes involved in ulcerative colitis (UC), Crohn’s disease (CD), and their extra-intestinal manifestations. METHODS: Protein coding genes involved in ulcerative colitis (3783 genes), Crohn’s disease (3980 genes), uveitis (1043 genes), arthritis (...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mohan, Sachin, Mok, Shaffer, Judge, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Rapid Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585167/ https://www.ncbi.nlm.nih.gov/pubmed/33116744 http://dx.doi.org/10.2147/CEG.S264812

Ejemplares similares

Identification of galectin-3 as a novel potential prognostic/predictive biomarker and therapeutic target for cerebral cavernous malformation disease
por: Kar, Souvik, et al.
Publicado: (2023)

CCR7 as a novel therapeutic target in t-cell PROLYMPHOCYTIC leukemia
por: Cuesta-Mateos, Carlos, et al.
Publicado: (2020)

DEFB1 gene 5′ untranslated region (UTR) polymorphisms in inflammatory bowel diseases
por: Zanin, Valentina, et al.
Publicado: (2012)

Microtubule actin crosslinking factor 1 functions as a novel therapeutic target in lung metastasis of osteosarcoma
por: Yang, Chaofei, et al.
Publicado: (2022)

Molecular identification of genus Duttaphrynus from Punjab, Pakistan
por: Hussain, Saddam, et al.
Publicado: (2020)

Human RNA Modifications Disease Database (HRMDD): A web resource for the molecular and clinical landscape of RNA modifications in human diseases
por: Wang, Jianjian, et al.
Publicado: (2022)

Targeted nanopore sequencing for the identification of novel PRMT1 circRNAs unveils a diverse transcriptional profile of this gene in breast cancer cells
por: Papatsirou, Maria, et al.
Publicado: (2023)

Identification of mitochondria-related action targets of quercetin in melanoma cells
por: Xi, Qing, et al.
Publicado: (2023)

Five personality dimensions in patients with irritable bowel syndrome
por: Farnam, Alireza, et al.
Publicado: (2008)

Molecular approach for identification of Catla catla using mitochondrial CO1 from Pakistan
por: Naeem, Zara, et al.
Publicado: (2020)

Molecular identification of Aquilaria species with distribution records in China using DNA barcode technology
por: Kang, Yong
Publicado: (2021)

Deoxynivalenol-sulfates: identification and quantification of novel conjugated (masked) mycotoxins in wheat
por: Warth, Benedikt, et al.
Publicado: (2014)

Molecular Genetic Diagnosis of von Hippel‐Lindau Disease: Analysis of Five Japanese Families
por: Kanno, Hiroshi, et al.
Publicado: (1996)

Identification of a novel pathogenic variant in FBN1 associated with Marfan syndrome
por: Pereira, Julia P., et al.
Publicado: (2022)

A heuristic approach to handling missing data in biologics manufacturing databases
por: Mante, Jeanet, et al.
Publicado: (2019)

Highlighting novel genes associated with the classical Rett syndrome patient from India
por: Mohan, Gomathi, et al.
Publicado: (2022)

Targeted NGS analysis reveals a complex genetic background of idiopathic erythrocytosis in a large Venetian family
por: Bertozzi, Irene, et al.
Publicado: (2023)

Identification of Novel Mutations in STAR Gene in Patients with Lipoid Congenital Adrenal Hyperplasia: A First Report from India
por: Vasudevan, Lakshmi, et al.
Publicado: (2013)

Identification of a novel MYOC variant in a Hispanic family with early-onset primary open-angle glaucoma with elevated intraocular pressure
por: Criscione, June, et al.
Publicado: (2019)

A novel variant of GALC in a familial case of Krabbe disease: Insights from structural bioinformatics and molecular dynamics simulation
por: Ullah, Ikram, et al.
Publicado: (2023)

SARS-CoV-2 vaccination for patients with inflammatory bowel disease: a British Society of Gastroenterology Inflammatory Bowel Disease section and IBD Clinical Research Group position statement
por: Alexander, James L, et al.
Publicado: (2021)

Thyroid as a target of adjuvant autoimmunity/inflammatory syndrome due to mRNA-based SARS-CoV2 vaccination: from Graves’ disease to silent thyroiditis
por: Pujol, A., et al.
Publicado: (2021)

Dehydrozaluzanin C, a novel type of anti-bacterial agent which targets transporting proteins, Opp and OpuC
por: Qin, Xiangyang, et al.
Publicado: (2021)

An epidemic CC1-MRSA-IV clone yields false-negative test results in molecular MRSA identification assays: a note of caution, Austria, Germany, Ireland, 2020
por: Monecke, Stefan, et al.
Publicado: (2020)

Consequences of the discontinuation of the International Protein Index (IPI) database and its substitution by the UniProtKB “complete proteome” sets
por: Griss, Johannes, et al.
Publicado: (2011)

Pathogenicity and genetic characterisation of a novel reassortant, highly pathogenic avian influenza (HPAI) H5N6 virus isolated in Korea, 2017
por: Kim, Young-Il, et al.
Publicado: (2018)

Genetic characterisation of novel, highly pathogenic avian influenza (HPAI) H5N6 viruses isolated in birds, South Korea, November 2016
por: Si, Young-Jae, et al.
Publicado: (2017)

Novel pan-lineage VP1 specific degenerate primers for precise genetic characterization of serotype O foot and mouth disease virus circulating in India
por: Khulape, Sagar Ashok, et al.
Publicado: (2023)

Transcatheter Aortic Valve Implantation and Surgical Aortic Valve Replacement for Aortic Stenosis in Japan　― Analysis of a Nationwide Inpatient Database ―
por: Kamon, Tatsuya, et al.
Publicado: (2020)

Endoscopy in inflammatory bowel diseases during the COVID-19 pandemic and post-pandemic period
por: Iacucci, Marietta, et al.
Publicado: (2020)

Identification and evolution of avian endogenous foamy viruses
por: Chen, Yicong, et al.
Publicado: (2019)

Comparison of outcomes of different biopsy schedules among men on active surveillance for prostate cancer: An analysis of the G.A.P.3 global consortium database
por: Beckmann, Kerri R., et al.
Publicado: (2022)

Nanomembrane-driven co-elution and integration of active chemotherapeutic and anti-inflammatory agents
por: Pierstorff, Erik, et al.
Publicado: (2008)

Discovery of an effective anti-inflammatory agent for inhibiting the activation of NF-κB
por: Yan, Yaoyao, et al.
Publicado: (2023)

The genetic variations in the mitochondrial genomes of three Luciolinae fireflies
por: Liu, Quan, et al.
Publicado: (2020)

Identification of Genes Associated with the Progression of Adult T Cell Leukemia (ATL)
por: Kohno, Tomoko, et al.
Publicado: (2000)

Identification of a mimotope of an infectious bronchitis virus S1 protein
por: Zhou, Jingming, et al.
Publicado: (2021)

Anti-inflammatory effects of intravenous methotrexate associated with lipid nanoemulsions on antigen-induced arthritis
por: Mello, Suzana B V, et al.
Publicado: (2016)

Study on the use of omega-3 fatty acids as a therapeutic supplement in treatment of psoriasis
por: Balbás, G Márquez, et al.
Publicado: (2011)

Thrombolysis treatment for submassive pulmonary thromboembolism in patients with cancer: a safe therapeutic tool
por: de Almeida, Juliano Pinheiro, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_uj20bmrcd6o0370jlr80bh71lp