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Long interspersed nuclear element 1 hypomethylation has novel prognostic value and potential utility in liquid biopsy for oral cavity cancer
BACKGROUND: New biomarkers are urgently needed to improve personalized treatment approaches for head and neck squamous cell carcinoma (HNSCC). Global DNA hypomethylation has wide-ranging functions in multistep carcinogenesis, and the hypomethylation of long interspersed nucleotide element-1 (LINE-1)...
Autores principales: | Misawa, Kiyoshi, Yamada, Satoshi, Mima, Masato, Nakagawa, Takuya, Kurokawa, Tomoya, Imai, Atsushi, Mochizuki, Daiki, Shinmura, Daichi, Yamada, Taiki, Kita, Junya, Ishikawa, Ryuji, Yamaguchi, Yuki, Misawa, Yuki, Kanazawa, Takeharu, Kawasaki, Hideya, Mineta, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585304/ https://www.ncbi.nlm.nih.gov/pubmed/33110605 http://dx.doi.org/10.1186/s40364-020-00235-y |
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