Case Report: Overwhelming Babesia Parasitemia Successfully Treated Promptly With RBC Apheresis and Triple Therapy With Clindamycin, Azithromycin, and Atovaquone

Babesiosis with high-grade parasitemia is life-threatening, especially in asplenic hosts. We report an asplenic patient with parasitemia >50% who was successfully treated with prompt red blood cell apheresis and triple therapy with clindamycin + azithromycin + atovaquone. This regimen may be an a...

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Detalles Bibliográficos
Autores principales: Li, Yijia, Stanley, Susan, Villalba, Julian A, Nelson, Sandra, Gelfand, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Novel ID Cases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585322/
https://www.ncbi.nlm.nih.gov/pubmed/33134419
http://dx.doi.org/10.1093/ofid/ofaa448
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author Li, Yijia
Stanley, Susan
Villalba, Julian A
Nelson, Sandra
Gelfand, Jeffrey
author_facet Li, Yijia
Stanley, Susan
Villalba, Julian A
Nelson, Sandra
Gelfand, Jeffrey
author_sort Li, Yijia
collection PubMed
description Babesiosis with high-grade parasitemia is life-threatening, especially in asplenic hosts. We report an asplenic patient with parasitemia >50% who was successfully treated with prompt red blood cell apheresis and triple therapy with clindamycin + azithromycin + atovaquone. This regimen may be an alternative to poorly tolerated clindamycin + quinine in severe cases.
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spelling pubmed-75853222020-10-29 Case Report: Overwhelming Babesia Parasitemia Successfully Treated Promptly With RBC Apheresis and Triple Therapy With Clindamycin, Azithromycin, and Atovaquone Li, Yijia Stanley, Susan Villalba, Julian A Nelson, Sandra Gelfand, Jeffrey Open Forum Infect Dis Novel ID Cases Babesiosis with high-grade parasitemia is life-threatening, especially in asplenic hosts. We report an asplenic patient with parasitemia >50% who was successfully treated with prompt red blood cell apheresis and triple therapy with clindamycin + azithromycin + atovaquone. This regimen may be an alternative to poorly tolerated clindamycin + quinine in severe cases. Oxford University Press 2020-09-23 /pmc/articles/PMC7585322/ /pubmed/33134419 http://dx.doi.org/10.1093/ofid/ofaa448 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Novel ID Cases
Li, Yijia
Stanley, Susan
Villalba, Julian A
Nelson, Sandra
Gelfand, Jeffrey
Case Report: Overwhelming Babesia Parasitemia Successfully Treated Promptly With RBC Apheresis and Triple Therapy With Clindamycin, Azithromycin, and Atovaquone
title Case Report: Overwhelming Babesia Parasitemia Successfully Treated Promptly With RBC Apheresis and Triple Therapy With Clindamycin, Azithromycin, and Atovaquone
title_full Case Report: Overwhelming Babesia Parasitemia Successfully Treated Promptly With RBC Apheresis and Triple Therapy With Clindamycin, Azithromycin, and Atovaquone
title_fullStr Case Report: Overwhelming Babesia Parasitemia Successfully Treated Promptly With RBC Apheresis and Triple Therapy With Clindamycin, Azithromycin, and Atovaquone
title_full_unstemmed Case Report: Overwhelming Babesia Parasitemia Successfully Treated Promptly With RBC Apheresis and Triple Therapy With Clindamycin, Azithromycin, and Atovaquone
title_short Case Report: Overwhelming Babesia Parasitemia Successfully Treated Promptly With RBC Apheresis and Triple Therapy With Clindamycin, Azithromycin, and Atovaquone
title_sort case report: overwhelming babesia parasitemia successfully treated promptly with rbc apheresis and triple therapy with clindamycin, azithromycin, and atovaquone
topic Novel ID Cases
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585322/
https://www.ncbi.nlm.nih.gov/pubmed/33134419
http://dx.doi.org/10.1093/ofid/ofaa448
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