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The desensitization pathway of GABA(A) receptors, one subunit at a time
GABA(A) receptors mediate most inhibitory synaptic transmission in the brain of vertebrates. Following GABA binding and fast activation, these receptors undergo a slower desensitization, the conformational pathway of which remains largely elusive. To explore the mechanism of desensitization, we used...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585415/ https://www.ncbi.nlm.nih.gov/pubmed/33097732 http://dx.doi.org/10.1038/s41467-020-19218-6 |