Nanocompartments work as tiny loudspeakers to amplify cell signalling behaviour

Aberrant cell signalling has been associated with a number of diseases. Belluati and coworkers make use of dual polymer nanocompartments encapsulating different enzymes, that function in unison as in a native signalling cascade. Their functionality is integrated into native cell metabolism and physi...

Descripción completa

Detalles Bibliográficos
Autor principal: Akhtar, Anam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585418/
https://www.ncbi.nlm.nih.gov/pubmed/33097831
http://dx.doi.org/10.1038/s42003-020-01352-y
_version_ 1783599786271703040
author Akhtar, Anam
author_facet Akhtar, Anam
author_sort Akhtar, Anam
collection PubMed
description Aberrant cell signalling has been associated with a number of diseases. Belluati and coworkers make use of dual polymer nanocompartments encapsulating different enzymes, that function in unison as in a native signalling cascade. Their functionality is integrated into native cell metabolism and physiology, using substrates already present in the extracellular medium. They succeed in amplifying a natural signalling cascade and influencing cellular homoeostasis.
format Online
Article
Text
id pubmed-7585418
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-75854182020-10-26 Nanocompartments work as tiny loudspeakers to amplify cell signalling behaviour Akhtar, Anam Commun Biol Research Highlight Aberrant cell signalling has been associated with a number of diseases. Belluati and coworkers make use of dual polymer nanocompartments encapsulating different enzymes, that function in unison as in a native signalling cascade. Their functionality is integrated into native cell metabolism and physiology, using substrates already present in the extracellular medium. They succeed in amplifying a natural signalling cascade and influencing cellular homoeostasis. Nature Publishing Group UK 2020-10-23 /pmc/articles/PMC7585418/ /pubmed/33097831 http://dx.doi.org/10.1038/s42003-020-01352-y Text en © Springer Nature Limited 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Highlight
Akhtar, Anam
Nanocompartments work as tiny loudspeakers to amplify cell signalling behaviour
title Nanocompartments work as tiny loudspeakers to amplify cell signalling behaviour
title_full Nanocompartments work as tiny loudspeakers to amplify cell signalling behaviour
title_fullStr Nanocompartments work as tiny loudspeakers to amplify cell signalling behaviour
title_full_unstemmed Nanocompartments work as tiny loudspeakers to amplify cell signalling behaviour
title_short Nanocompartments work as tiny loudspeakers to amplify cell signalling behaviour
title_sort nanocompartments work as tiny loudspeakers to amplify cell signalling behaviour
topic Research Highlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585418/
https://www.ncbi.nlm.nih.gov/pubmed/33097831
http://dx.doi.org/10.1038/s42003-020-01352-y
work_keys_str_mv AT akhtaranam nanocompartmentsworkastinyloudspeakerstoamplifycellsignallingbehaviour

Ejemplares similares