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A numerical study of pre-polarisation switching in ultra-low field magnetic resonance imaging using dynamic permanent magnet arrays

Dynamically adjustable permanent magnet arrays have been proposed to generate switchable magnetic fields for pre-polarisation in Ultra-Low Field magnetic resonance imaging. However, the optimal switching dynamics of the pre-polarisation magnetic field as well as the energy requirements, mechanical f...

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Autores principales: Pellicer-Guridi, Ruben, Vogel, Michael W., Vegh, Viktor, Su, Jiasheng, Rosen, Matthew S., Reutens, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585444/
https://www.ncbi.nlm.nih.gov/pubmed/33097737
http://dx.doi.org/10.1038/s41598-020-74931-y
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author Pellicer-Guridi, Ruben
Vogel, Michael W.
Vegh, Viktor
Su, Jiasheng
Rosen, Matthew S.
Reutens, David C.
author_facet Pellicer-Guridi, Ruben
Vogel, Michael W.
Vegh, Viktor
Su, Jiasheng
Rosen, Matthew S.
Reutens, David C.
author_sort Pellicer-Guridi, Ruben
collection PubMed
description Dynamically adjustable permanent magnet arrays have been proposed to generate switchable magnetic fields for pre-polarisation in Ultra-Low Field magnetic resonance imaging. However, the optimal switching dynamics of the pre-polarisation magnetic field as well as the energy requirements, mechanical forces and stresses during switching of the pre-polarisation field have not been evaluated. We analysed these requirements numerically and estimated the magnetic resonance signal strength and image quality for two practical switching modes in an instrument suitable for scanning the human head. Von Mises stress analysis showed that although magnetic forces were significantly higher for two specific rungs, the structural integrity of magnet rungs would not be compromised. Our simulations suggest that a significantly higher signal yield is obtained by switching off the pre-polarisation field with the angular velocity in each rung dependent on its location.
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spelling pubmed-75854442020-10-27 A numerical study of pre-polarisation switching in ultra-low field magnetic resonance imaging using dynamic permanent magnet arrays Pellicer-Guridi, Ruben Vogel, Michael W. Vegh, Viktor Su, Jiasheng Rosen, Matthew S. Reutens, David C. Sci Rep Article Dynamically adjustable permanent magnet arrays have been proposed to generate switchable magnetic fields for pre-polarisation in Ultra-Low Field magnetic resonance imaging. However, the optimal switching dynamics of the pre-polarisation magnetic field as well as the energy requirements, mechanical forces and stresses during switching of the pre-polarisation field have not been evaluated. We analysed these requirements numerically and estimated the magnetic resonance signal strength and image quality for two practical switching modes in an instrument suitable for scanning the human head. Von Mises stress analysis showed that although magnetic forces were significantly higher for two specific rungs, the structural integrity of magnet rungs would not be compromised. Our simulations suggest that a significantly higher signal yield is obtained by switching off the pre-polarisation field with the angular velocity in each rung dependent on its location. Nature Publishing Group UK 2020-10-23 /pmc/articles/PMC7585444/ /pubmed/33097737 http://dx.doi.org/10.1038/s41598-020-74931-y Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Pellicer-Guridi, Ruben
Vogel, Michael W.
Vegh, Viktor
Su, Jiasheng
Rosen, Matthew S.
Reutens, David C.
A numerical study of pre-polarisation switching in ultra-low field magnetic resonance imaging using dynamic permanent magnet arrays
title A numerical study of pre-polarisation switching in ultra-low field magnetic resonance imaging using dynamic permanent magnet arrays
title_full A numerical study of pre-polarisation switching in ultra-low field magnetic resonance imaging using dynamic permanent magnet arrays
title_fullStr A numerical study of pre-polarisation switching in ultra-low field magnetic resonance imaging using dynamic permanent magnet arrays
title_full_unstemmed A numerical study of pre-polarisation switching in ultra-low field magnetic resonance imaging using dynamic permanent magnet arrays
title_short A numerical study of pre-polarisation switching in ultra-low field magnetic resonance imaging using dynamic permanent magnet arrays
title_sort numerical study of pre-polarisation switching in ultra-low field magnetic resonance imaging using dynamic permanent magnet arrays
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585444/
https://www.ncbi.nlm.nih.gov/pubmed/33097737
http://dx.doi.org/10.1038/s41598-020-74931-y
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