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The genetic architecture of appendicular lean mass characterized by association analysis in the UK Biobank study

Appendicular lean mass (ALM) is a heritable trait associated with loss of lean muscle mass and strength, or sarcopenia, but its genetic determinants are largely unknown. Here we conducted a genome-wide association study (GWAS) with 450,243 UK Biobank participants to uncover its genetic architecture....

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Detalles Bibliográficos
Autores principales: Pei, Yu-Fang, Liu, Yao-Zhong, Yang, Xiao-Lin, Zhang, Hong, Feng, Gui-Juan, Wei, Xin-Tong, Zhang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585446/
https://www.ncbi.nlm.nih.gov/pubmed/33097823
http://dx.doi.org/10.1038/s42003-020-01334-0