Cargando…

The genetic architecture of appendicular lean mass characterized by association analysis in the UK Biobank study

Appendicular lean mass (ALM) is a heritable trait associated with loss of lean muscle mass and strength, or sarcopenia, but its genetic determinants are largely unknown. Here we conducted a genome-wide association study (GWAS) with 450,243 UK Biobank participants to uncover its genetic architecture....

Descripción completa

Detalles Bibliográficos
Autores principales:	Pei, Yu-Fang, Liu, Yao-Zhong, Yang, Xiao-Lin, Zhang, Hong, Feng, Gui-Juan, Wei, Xin-Tong, Zhang, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585446/ https://www.ncbi.nlm.nih.gov/pubmed/33097823 http://dx.doi.org/10.1038/s42003-020-01334-0

Ejemplares similares

Genome-Wide Association Study Identified Copy Number Variants Important for Appendicular Lean Mass
por: Ran, Shu, et al.
Publicado: (2014)

Frailty, appendicular lean mass, osteoporosis and osteosarcopenia in peritoneal dialysis patients
por: Davenport, Andrew
Publicado: (2022)

Development of Novel Methods to Define Deficits in Appendicular Lean Mass Relative to Fat Mass
por: Weber, David, et al.
Publicado: (2016)

Bivariate Genome-Wide Association Analyses of Femoral Neck Bone Geometry and Appendicular Lean Mass
por: Sun, Lu, et al.
Publicado: (2011)

Insulin Resistance in Early Rheumatoid Arthritis Is Associated with Low Appendicular Lean Mass
por: Müller, Raili, et al.
Publicado: (2017)

Equations for smartphone prediction of adiposity and appendicular lean mass in youth soccer players
por: Minetto, Marco A., et al.
Publicado: (2023)

Two-megahertz impedance index prediction equation for appendicular lean mass in Korean older people
por: Kim, Hyeoijin, et al.
Publicado: (2022)

Cutpoints for Low Appendicular Lean Mass That Identify Older Adults With Clinically Significant Weakness
por: Cawthon, Peggy M., et al.
Publicado: (2014)

Development of a bedside viable ultrasound protocol to quantify appendicular lean tissue mass
por: Paris, Michael T., et al.
Publicado: (2017)

Identification of three bacterial species associated with increased appendicular lean mass: the HUNT study
por: Grahnemo, Louise, et al.
Publicado: (2023)

Changes in predicted lean body mass, appendicular skeletal muscle mass, and body fat mass and cardiovascular disease
por: Kim, Seong Rae, et al.
Publicado: (2022)

Correction: Two-megahertz impedance index prediction equation for appendicular lean mass in Korean older people
por: Kim, Hyeoijin, et al.
Publicado: (2022)

Development and validation of anthropometric prediction equations for estimation of lean body mass and appendicular lean soft tissue in Indian men and women
por: Kulkarni, Bharati, et al.
Publicado: (2013)

Appendicular foreign body presenting with appendicular mass
por: Chou, Andy Shau-Bin, et al.
Publicado: (2016)

Shared genetic architecture of blood eosinophil counts and asthma in UK Biobank
por: Li, Boyang, et al.
Publicado: (2023)

Toward a sex-specific relationship between muscle strength and appendicular lean body mass index?
por: Barbat-Artigas, Sébastien, et al.
Publicado: (2013)

What is the best adjustment of appendicular lean mass for predicting mortality or disability among Japanese community dwellers?
por: Otsuka, Rei, et al.
Publicado: (2018)

Enhanced Identification of Novel Potential Variants for Appendicular Lean Mass by Leveraging Pleiotropy With Bone Mineral Density
por: Peng, Cheng, et al.
Publicado: (2021)

Appendicular Lean Mass, Grip Strength, and the Development of Knee Osteoarthritis and Knee Pain Among Older Adults
por: Andrews, James S., et al.
Publicado: (2021)

Association of the triglyceride-glucose index with weight-adjusted appendicular lean mass in Chinese adolescents aged 12–18 years old
por: Zhou, Jinyu, et al.
Publicado: (2022)

Appendicular Band Syndrome simulating Appendicular Mass in a Child
por: Mirza, Bilal, et al.
Publicado: (2014)

Characterizing the phenotypic and genetic structure of psychopathology in UK Biobank
por: Williams, Camille M., et al.
Publicado: (2023)

Appendicular Lean Mass Loss Does Not Impact Physical Performance Change During Caloric Restriction in Older Adults
por: Beavers, Daniel, et al.
Publicado: (2021)

Frequency and Functional Consequences of Low Appendicular Lean Mass and Sarcopenic Obesity in Patients with Asthma Referred for Pulmonary Rehabilitation
por: Meys, Roy, et al.
Publicado: (2023)

Shared genetic architecture between mental health and the brain functional connectome in the UK Biobank
por: Roelfs, Daniel, et al.
Publicado: (2023)

Laparoscopic management of appendicular mass
por: Shindholimath, Vishwanath V, et al.
Publicado: (2011)

Comparison of appendicular lean mass indices for predicting physical performance in Korean hemodialysis patients: A cross-sectional study
por: Kim, Jun Chul, et al.
Publicado: (2021)

Association between the appendicular lean mass index or handgrip strength and bone mineral density in patients undergoing peritoneal dialysis
por: Kang, Seok Hui, et al.
Publicado: (2022)

Bio-Electrical Impedance Analysis: A Valid Assessment Tool for Diagnosis of Low Appendicular Lean Mass in Older Adults?
por: van den Helder, Jantine, et al.
Publicado: (2022)

Two functional variants at 6p21.1 were associated with lean mass
por: Pei, Yu-Fang, et al.
Publicado: (2019)

Genome-Wide Association Study and Genetic Correlation Scan Provide Insights into Its Genetic Architecture of Sleep Health Score in the UK Biobank Cohort
por: Yao, Yao, et al.
Publicado: (2022)

Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis
por: Zengini, Eleni, et al.
Publicado: (2018)

Adiponectin Is a Contributing Factor of Low Appendicular Lean Mass in Older Community-Dwelling Women: A Cross-Sectional Study
por: Teixeira, Leonardo Augusto Costa, et al.
Publicado: (2022)

Genetic stratification of depression in UK Biobank
por: Howard, David M., et al.
Publicado: (2020)

Caecal tumour masquerading as an appendicular mass
por: Nixon, Martha, et al.
Publicado: (2011)

Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection
por: Schoech, Armin P., et al.
Publicado: (2019)

Associations of protein source, distribution and healthy dietary pattern with appendicular lean mass in oldest-old men: the Helsinki Businessmen Study (HBS)
por: Jyväkorpi, S. K., et al.
Publicado: (2020)

Association between appendicular lean mass and chronic obstructive pulmonary disease: epidemiological cross-sectional study and bidirectional Mendelian randomization analysis
por: Fu, Chengjie, et al.
Publicado: (2023)

Genetic predisposition to tinnitus in the UK Biobank population
por: Urbanek, Madeleine E., et al.
Publicado: (2021)

Characterizing the hypertensive cardiovascular phenotype in the UK Biobank
por: Elghazaly, Hussein, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_k2c2v5v5c9bao39vtvqepqvrnh