Evaluation the interaction of ABC multidrug transporter MDR1 with thymoquinone: substrate or inhibitor?

OBJECTIVE(S): Thymoquinone (TQ) has valuable medical properties like anticancer effects. Development of multidrug resistance (MDR) phenotype is one of the most important factors in failure of cancer chemotherapy. The aim of this study was to evaluate the mode of interaction of TQ and MDR1, a major M...

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Detalles Bibliográficos
Autores principales: Keyvani, Vahideh, Nasserifar, Zeinab, Saberi, Mohammad-Reza, Mohajeri, Seyed Ahmad, Arabzadeh, Sepideh, Shahriari Ahmadi, Farajollah, Hosseinzadeh, Hossein, Shariat Razavi, Seyedeh Mahya, Kalalinia, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585528/
https://www.ncbi.nlm.nih.gov/pubmed/33149871
http://dx.doi.org/10.22038/ijbms.2020.44216.10381

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