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The importance of specialized sleep investigations in children with a suprasellar tumor
PURPOSE: Disruption of sleep has great impact on quality of life. In children with a suprasellar tumor and hypothalamic-pituitary dysfunction, the circadian rhythm may be disturbed causing sleep problems. However, also other factors may influence sleep. Awareness of these different etiologies and ca...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585563/ https://www.ncbi.nlm.nih.gov/pubmed/32691357 http://dx.doi.org/10.1007/s11102-020-01065-9 |
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author | van Schaik, J. Pillen, S. van Litsenburg, R. R. L. Vandenbussche, N. L. E. de Bont, J. M. Schouten-van Meeteren, A. Y. N. van Santen, H. M. |
author_facet | van Schaik, J. Pillen, S. van Litsenburg, R. R. L. Vandenbussche, N. L. E. de Bont, J. M. Schouten-van Meeteren, A. Y. N. van Santen, H. M. |
author_sort | van Schaik, J. |
collection | PubMed |
description | PURPOSE: Disruption of sleep has great impact on quality of life. In children with a suprasellar tumor and hypothalamic-pituitary dysfunction, the circadian rhythm may be disturbed causing sleep problems. However, also other factors may influence sleep. Awareness of these different etiologies and careful history taking with appropriate additional diagnostics will aid in restoring sleep quality. METHODS: We present the workup of 4 cases with a suprasellar tumor and disturbances of sleep initiation, sleep maintenance, and daytime sleepiness. In parallel, we developed a flowchart, to aid clinicians in the diagnostics of sleep problems in children after treatment for a (supra) sellar brain tumor. RESULTS: All four patients, known with hypopituitarism, presented with sleep complaints and increased daytime sleepiness. In all four, the cause of sleep problems showed to be different. In the first case, sleep evaluation revealed a severe obstructive sleep apnea, whereupon nocturnal ventilation was started. The second case revealed poor sleep hygiene in combination with an obsessive compulsive disorder. Sleep hygiene was addressed and psychiatric consultation was offered. Dexamphetamine treatment was started to reduce her obsessive compulsive complaints. The third case showed a delayed sleep phase syndrome, which improved by educational support. The fourth case revealed a secondary organic hypersomnia for which modafinil treatment was started. CONCLUSION: Sleep disturbances in children with hypopituitarism due to a (supra) sellar tumor can have different entities which require specific therapy. Awareness of these different entities is important to enable appropriate counseling. Referral to an expertise sleep center may be advised, if standard educational support is insufficient. |
format | Online Article Text |
id | pubmed-7585563 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-75855632020-11-03 The importance of specialized sleep investigations in children with a suprasellar tumor van Schaik, J. Pillen, S. van Litsenburg, R. R. L. Vandenbussche, N. L. E. de Bont, J. M. Schouten-van Meeteren, A. Y. N. van Santen, H. M. Pituitary Article PURPOSE: Disruption of sleep has great impact on quality of life. In children with a suprasellar tumor and hypothalamic-pituitary dysfunction, the circadian rhythm may be disturbed causing sleep problems. However, also other factors may influence sleep. Awareness of these different etiologies and careful history taking with appropriate additional diagnostics will aid in restoring sleep quality. METHODS: We present the workup of 4 cases with a suprasellar tumor and disturbances of sleep initiation, sleep maintenance, and daytime sleepiness. In parallel, we developed a flowchart, to aid clinicians in the diagnostics of sleep problems in children after treatment for a (supra) sellar brain tumor. RESULTS: All four patients, known with hypopituitarism, presented with sleep complaints and increased daytime sleepiness. In all four, the cause of sleep problems showed to be different. In the first case, sleep evaluation revealed a severe obstructive sleep apnea, whereupon nocturnal ventilation was started. The second case revealed poor sleep hygiene in combination with an obsessive compulsive disorder. Sleep hygiene was addressed and psychiatric consultation was offered. Dexamphetamine treatment was started to reduce her obsessive compulsive complaints. The third case showed a delayed sleep phase syndrome, which improved by educational support. The fourth case revealed a secondary organic hypersomnia for which modafinil treatment was started. CONCLUSION: Sleep disturbances in children with hypopituitarism due to a (supra) sellar tumor can have different entities which require specific therapy. Awareness of these different entities is important to enable appropriate counseling. Referral to an expertise sleep center may be advised, if standard educational support is insufficient. Springer US 2020-07-20 2020 /pmc/articles/PMC7585563/ /pubmed/32691357 http://dx.doi.org/10.1007/s11102-020-01065-9 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article van Schaik, J. Pillen, S. van Litsenburg, R. R. L. Vandenbussche, N. L. E. de Bont, J. M. Schouten-van Meeteren, A. Y. N. van Santen, H. M. The importance of specialized sleep investigations in children with a suprasellar tumor |
title | The importance of specialized sleep investigations in children with a suprasellar tumor |
title_full | The importance of specialized sleep investigations in children with a suprasellar tumor |
title_fullStr | The importance of specialized sleep investigations in children with a suprasellar tumor |
title_full_unstemmed | The importance of specialized sleep investigations in children with a suprasellar tumor |
title_short | The importance of specialized sleep investigations in children with a suprasellar tumor |
title_sort | importance of specialized sleep investigations in children with a suprasellar tumor |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585563/ https://www.ncbi.nlm.nih.gov/pubmed/32691357 http://dx.doi.org/10.1007/s11102-020-01065-9 |
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