Cargando…

Weighted gene co-expression network analysis revealed key biomarkers associated with the diagnosis of hypertrophic cardiomyopathy

OBJECTIVE: To reveal the molecular mechanism underlying the pathogenesis of HCM and find new effective therapeutic strategies using a systematic biological approach. METHODS: The WGCNA algorithm was applied to building the co-expression network of HCM samples. A sample cluster analysis was performed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Xin, Wang, Chenxin, Zhang, Xiaoqing, Liu, Jiali, Wang, Yu, Li, Chunpu, Guo, Dongmei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585681/ https://www.ncbi.nlm.nih.gov/pubmed/33099311 http://dx.doi.org/10.1186/s41065-020-00155-9

Ejemplares similares

T2-weighted cardiac magnetic resonance image and myocardial biomarker in hypertrophic cardiomyopathy
por: Chen, Shi, et al.
Publicado: (2020)

Circulating Biomarkers in Hypertrophic Cardiomyopathy
por: Matthia, Eldon L., et al.
Publicado: (2022)

Diagnosis and management of hypertrophic cardiomyopathy
por: Pantazis, Antonis, et al.
Publicado: (2015)

DNA methylome and transcriptome profiling reveal key electrophysiology and immune dysregulation in hypertrophic cardiomyopathy
por: Li, Xiaoyan, et al.
Publicado: (2023)

Identification of key proteins and lncRNAs in hypertrophic cardiomyopathy by integrated network analysis
por: Hu, Xiaofeng, et al.
Publicado: (2018)

Reconstruction and analysis of potential biomarkers for hypertrophic cardiomyopathy based on a competing endogenous RNA network
por: Chen, Jin-yan, et al.
Publicado: (2022)

Familial Hypertrophic Cardiomyopathy: Diagnosis and Management
por: Litt, Michael J, et al.
Publicado: (2023)

Identification and analysis of key hypoxia- and immune-related genes in hypertrophic cardiomyopathy
por: Yu, Haozhen, et al.
Publicado: (2023)

Rapid molecular genetic diagnosis of hypertrophic cardiomyopathy by semiconductor sequencing
por: Li, Zongzhe, et al.
Publicado: (2014)

Bioinformatics and Immune Infiltration Analyses Reveal the Key Pathway and Immune Cells in the Pathogenesis of Hypertrophic Cardiomyopathy
por: Zhang, Xu-Zhe, et al.
Publicado: (2021)

The diagnosis of hypertrophic cardiomyopathy by cardiovascular magnetic resonance
por: Noureldin, Radwa A, et al.
Publicado: (2012)

Echocardiographic diagnosis of the different phenotypes of hypertrophic cardiomyopathy
por: Parato, Vito Maurizio, et al.
Publicado: (2016)

Hypertrophic cardiomyopathy
por: Antunes, Murillo de Oliveira, et al.
Publicado: (2020)

Hypertrophic Cardiomyopathy
por: Butt, Asra K., et al.
Publicado: (2023)

Biomarkers of cardiovascular stress and fibrosis in preclinical hypertrophic cardiomyopathy
por: Ho, Jennifer E, et al.
Publicado: (2017)

Dysfunctional Network and Mutation Genes of Hypertrophic Cardiomyopathy
por: Cui, Yunwen, et al.
Publicado: (2022)

Weight loss in hypertrophic cardiomyopathy: A clinical case series
por: Reuter, Maria C., et al.
Publicado: (2023)

Whole-Exome Sequencing Reveals Mutational Signature of Hypertrophic Cardiomyopathy
por: Wang, Xi-Qin, et al.
Publicado: (2023)

Identification of key biomarkers in ischemic stroke: single-cell sequencing and weighted co-expression network analysis
por: Tao, Jiali, et al.
Publicado: (2023)

Integration of transcriptomic data identifies key hallmark genes in hypertrophic cardiomyopathy
por: Xu, Jing, et al.
Publicado: (2021)

Apical hypertrophic cardiomyopathy: diagnosis, medical and surgical treatment
por: Paluszkiewicz, Jerzy, et al.
Publicado: (2018)

The role of echocardiography for diagnosis and prognostic stratification in hypertrophic cardiomyopathy
por: Mandeş, Leonard, et al.
Publicado: (2020)

Deep learning-based diagnosis of feline hypertrophic cardiomyopathy
por: Rho, Jinhyung, et al.
Publicado: (2023)

Identification of circulating hub long noncoding RNAs associated with hypertrophic cardiomyopathy using weighted correlation network analysis
por: Guo, Qi, et al.
Publicado: (2020)

Hypertrophic Midventricular Obstructive Cardiomyopathy Revealed by a Stroke
por: Habis, Michel, et al.
Publicado: (2019)

In vivo diffusion-weighted MRI detection of myocardial fibrosis in hypertrophic cardiomyopathy patients
por: Nguyen, Christopher T, et al.
Publicado: (2015)

The Feline Cardiomyopathies: 2. Hypertrophic cardiomyopathy
por: Kittleson, Mark D, et al.
Publicado: (2021)

The Establishment of Hypertrophic Cardiomyopathy Diagnosis Model via Artificial Neural Network and Random Decision Forest Method
por: Li, Shuanglei, et al.
Publicado: (2022)

Hypertrophic Obstructive Cardiomyopathy
por: Cohen, Lawrence S.
Publicado: (1972)

The genetics of hypertrophic cardiomyopathy
por: Akhtar, Mohammed, et al.
Publicado: (2018)

Disopyramide for Hypertrophic Cardiomyopathy
por: Sanchez-Nadales, Alejandro, et al.
Publicado: (2019)

What Causes Hypertrophic Cardiomyopathy?
por: Maron, Bradley A., et al.
Publicado: (2022)

Improving risk prediction in hypertrophic cardiomyopathy: the key role of Dutch founder variants
por: Walsh, R., et al.
Publicado: (2021)

Subaortic Membrane Co-existing With Hypertrophic Cardiomyopathy: A Clinically Challenging Diagnosis
por: Farhan, Mehr un Nisa, et al.
Publicado: (2022)

Identification of key genes for hypertrophic cardiomyopathy using integrated network analysis of differential lncRNA and gene expression
por: Cao, Jing, et al.
Publicado: (2022)

Genetics of hypertrophic cardiomyopathy: advances and pitfalls in molecular diagnosis and therapy
por: Roma-Rodrigues, Catarina, et al.
Publicado: (2014)

Post-Mortem Cardiac Magnetic Resonance for the Diagnosis of Hypertrophic Cardiomyopathy
por: Aquaro, Giovanni Donato, et al.
Publicado: (2020)

RNA Splicing Defects in Hypertrophic Cardiomyopathy: Implications for Diagnosis and Therapy
por: Ribeiro, Marta, et al.
Publicado: (2020)

Molecular Diagnosis of Hypertrophic Cardiomyopathy (HCM): In the Heart of Cardiac Disease
por: Melas, Marilena, et al.
Publicado: (2022)

Diagnosis and Clinical Implication of Left Ventricular Aneurysm in Hypertrophic Cardiomyopathy
por: Perillo, Errico Federico, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_q5u5rqrav3s0ktqu88jfr1l1bp