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ISL Induces Apoptosis and Autophagy in Hepatocellular Carcinoma via Downregulation of PI3K/AKT/mTOR Pathway in vivo and in vitro

AIMS: Isoliquiritigenin (ISL), a flavonoid from Glycyrrhiza glabra, has previously been reported to have anti-tumor effects in vivo and in vitro. However, the mechanisms whereby ISL exerts its anticancer effects remain poorly understood in hepatocellular carcinoma (HCC). PURPOSE: In the present stud...

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Detalles Bibliográficos
Autores principales: Song, Lei, Luo, Yi, Li, Shaoling, Hong, Ming, Wang, Qi, Chi, Xiaoling, Yang, Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585813/
https://www.ncbi.nlm.nih.gov/pubmed/33116421
http://dx.doi.org/10.2147/DDDT.S270124

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