Disulfiram, a Ferroptosis Inducer, Triggers Lysosomal Membrane Permeabilization by Up-Regulating ROS in Glioblastoma

INTRODUCTION: Disulfiram (DSF), a drug used in the treatment of alcoholism since 1948, has been shown to have antitumor properties in various tumor types possibly due to the induction of a type cell death, ferroptosis, and the sensitization of cells to chemo- and radiotherapy. In this study, we expl...

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Detalles Bibliográficos
Autores principales: Qiu, Chen, Zhang, Xin, Huang, Bin, Wang, Shuai, Zhou, Wenjing, Li, Chao, Li, Xingang, Wang, Jian, Yang, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585819/
https://www.ncbi.nlm.nih.gov/pubmed/33116640
http://dx.doi.org/10.2147/OTT.S272312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585819/
https://www.ncbi.nlm.nih.gov/pubmed/33116640
http://dx.doi.org/10.2147/OTT.S272312

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