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Deletion of NKX3.1 via CRISPR/Cas9 Induces Prostatic Intraepithelial Neoplasia in C57BL/6 Mice

Several techniques have been employed for deletion of the NKX3.1 gene, resulting in developmental defects of the prostate, including alterations in ductal branching morphogenesis and prostatic secretions as well as epithelial hyperplasia and dysplasia. To investigate whether the CRISPR/Cas9-mediated...

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Detalles Bibliográficos
Autores principales:	Park, Jin Ju, Kim, Ji Eun, Jeon, Yoon, Lee, Mi Rim, Choi, Jun Young, Song, Bo Ram, Park, Ji Won, Kang, Mi Ju, Choi, Hyeon Jun, Bae, Su Ji, Lee, Ho, Kang, Byeong Cheol, Hwang, Dae Youn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586030/ https://www.ncbi.nlm.nih.gov/pubmed/33094683 http://dx.doi.org/10.1177/1533033820964425

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