Cargando…

Lipin1 Is Involved in the Pathogenesis of Diabetic Encephalopathy through the PKD/Limk/Cofilin Signaling Pathway

Diabetic encephalopathy is a type of central diabetic neuropathy resulting from diabetes mainly manifested as cognitive impairments. However, its underlying pathogenesis and effective treatment strategies remain unclear. In the present study, we investigated the effect of Lipin1, a phosphatidic acid...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xie, Min, Wang, Meijian, Liu, Wei, Xu, Min, Shang, Pan, Jiang, Dongqing, Ju, Liping, Wu, Fei, Sun, Aili, Yu, Shuyan, Zhuang, Xianghua, Chen, Shihong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586151/ https://www.ncbi.nlm.nih.gov/pubmed/33123308 http://dx.doi.org/10.1155/2020/1723423

Ejemplares similares

Downregulation of LIMK1–ADF/cofilin by DADS inhibits the migration and invasion of colon cancer
por: Su, Jian, et al.
Publicado: (2017)

Neuroligin 1 regulates spines and synaptic plasticity via LIMK1/cofilin-mediated actin reorganization
por: Liu, An, et al.
Publicado: (2016)

Endoglin Is an Endothelial Housekeeper against Inflammation: Insight in ECFC-Related Permeability through LIMK/Cofilin Pathway
por: Rossi, Elisa, et al.
Publicado: (2021)

The Activation of the LIMK/Cofilin Signaling Pathway via Extracellular Matrix–Integrin Interactions Is Critical for the Generation of Mature and Vascularized Cardiac Organoids
por: Noh, Ji-Min, et al.
Publicado: (2023)

IP-10 Promotes Latent HIV Infection in Resting Memory CD4(+) T Cells via LIMK-Cofilin Pathway
por: Wang, Zhuo, et al.
Publicado: (2021)

Dichotomous effects of the cofilin kinase LIMK1 on the early steps of HIV-1 infection of CD4 T cells
por: Vorster, Paul J, et al.
Publicado: (2009)

MED12 exerts an emerging role in actin-mediated cytokinesis via LIMK2/cofilin pathway in NSCLC
por: Xu, Meng, et al.
Publicado: (2019)

BDNF Induced Translation of Limk1 in Developing Neurons Regulates Dendrite Growth by Fine-Tuning Cofilin1 Activity
por: Ravindran, Sreenath, et al.
Publicado: (2019)

Effects of PAK4/LIMK1/Cofilin‐1 signaling pathway on proliferation, invasion, and migration of human osteosarcoma cells
por: Li, Zhi‐Feng, et al.
Publicado: (2020)

Actin Dynamics, Regulated by RhoA-LIMK-Cofilin Signaling, Mediates Rod Photoreceptor Axonal Retraction After Retinal Injury
por: Wang, Weiwei, et al.
Publicado: (2019)

Cofilin-1, LIMK1 and SSH1 are differentially expressed in locally advanced colorectal cancer and according to consensus molecular subtypes
por: Sousa-Squiavinato, Annie Cristhine Moraes, et al.
Publicado: (2021)

The Wdr1-LIMK-Cofilin Axis Controls B Cell Antigen Receptor-Induced Actin Remodeling and Signaling at the Immune Synapse
por: Bolger-Munro, Madison, et al.
Publicado: (2021)

LMO3 promotes proliferation and metastasis of papillary thyroid carcinoma cells by regulating LIMK1-mediated cofilin and the β-catenin pathway
por: Ling, Zeyi, et al.
Publicado: (2022)

A Haspin-ARHGAP11A axis regulates epithelial morphogenesis through Rho-ROCK dependent modulation of LIMK1-Cofilin
por: Quadri, Roberto, et al.
Publicado: (2023)

Differential Roles of Lipin1 and Lipin2 in the Hepatitis C Virus Replication Cycle
por: Castro, Victoria, et al.
Publicado: (2019)

Role of lipins in cardiovascular diseases
por: Ding, Zerui, et al.
Publicado: (2023)

Pak1/LIMK1/Cofilin Pathway Contributes to Tumor Migration and Invasion in Human Non-Small Cell Lung Carcinomas and Cell Lines
por: Jang, Inseok, et al.
Publicado: (2012)

Diallyl disulfide induces downregulation and inactivation of cofilin 1 differentiation via the Rac1/ROCK1/LIMK1 pathway in leukemia cells
por: Ling, Hui, et al.
Publicado: (2020)

Alantolactone suppresses the metastatic phenotype and induces the apoptosis of glioblastoma cells by targeting LIMK kinase activity and activating the cofilin/G-actin signaling cascade
por: Wang, Xun, et al.
Publicado: (2021)

miR-137–LAPTM4B regulates cytoskeleton organization and cancer metastasis via the RhoA-LIMK-Cofilin pathway in osteosarcoma
por: Yan, Ruyu, et al.
Publicado: (2023)

FMNL2 suppresses cell migration and invasion of breast cancer: a reduction of cytoplasmic p27 via RhoA/LIMK/Cofilin pathway
por: Jiao, Xinyan, et al.
Publicado: (2022)

GPCR-mediated PLCβγ/PKCβ/PKD signaling pathway regulates the cofilin phosphatase slingshot 2 in neutrophil chemotaxis
por: Xu, Xuehua, et al.
Publicado: (2015)

Lipins cause a lamina breakdown
por: Leslie, Mitch
Publicado: (2012)

SphK2/S1P Promotes Metastasis of Triple-Negative Breast Cancer Through the PAK1/LIMK1/Cofilin1 Signaling Pathway
por: Shi, Weiwei, et al.
Publicado: (2021)

Changes in the central nervous system in diabetic neuropathy
por: Zang, Yarui, et al.
Publicado: (2023)

Deletion of Limk1 and Limk2 in mice does not alter cochlear development or auditory function
por: Fang, Qiaojun, et al.
Publicado: (2019)

The Function of Lipin in the Wing Development of Drosophila melanogaster
por: Duy Binh, Tran, et al.
Publicado: (2019)

DANCR promotes HCC progression and regulates EMT by sponging miR‐27a‐3p via ROCK1/LIMK1/COFILIN1 pathway
por: Guo, Dan, et al.
Publicado: (2019)

Structural Aspects of LIMK Regulation and Pharmacology
por: Chatterjee, Deep, et al.
Publicado: (2022)

Involvement of Macrophages in the Pathogenesis of Transmissible Spongiform Encephalopathies
por: Beringue, Vincent, et al.
Publicado: (2002)

LIMK1 and LIMK2 regulate cortical development through affecting neural progenitor cell proliferation and migration
por: Mao, Rui, et al.
Publicado: (2019)

LIM Kinases, LIMK1 and LIMK2, Are Crucial Node Actors of the Cell Fate: Molecular to Pathological Features
por: Villalonga, Elodie, et al.
Publicado: (2023)

Cardio(lipin) workout beefs up mitochondrial imports
por: Leslie, Mitch
Publicado: (2008)

Pkd1 and Pkd2 Are Required for Normal Placental Development
por: Garcia-Gonzalez, Miguel A., et al.
Publicado: (2010)

Cofilin Acts as a Booster for Progression of Malignant Tumors Represented by Glioma
por: Lv, Shihong, et al.
Publicado: (2022)

Cofilin, a Master Node Regulating Cytoskeletal Pathogenesis in Alzheimer’s Disease
por: Kang, David E., et al.
Publicado: (2019)

Temporal and Spatial Regulation of the Phosphatidate Phosphatases Lipin 1 and 2
por: Grimsey, Neil, et al.
Publicado: (2008)

Induction of Lipin1 by ROS-Dependent SREBP-2 Activation
por: Seo, Kyuhwa, et al.
Publicado: (2017)

Lipin-1 Contributes to IL-4 Mediated Macrophage Polarization
por: Chandran, Sunitha, et al.
Publicado: (2020)

Crystal structure of a lipin/Pah phosphatidic acid phosphatase
por: Khayyo, Valerie I., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_628gccn7hld97936k5mrv0i1kd