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Characterizing the binding and function of TARP γ8-selective AMPA receptor modulators

α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid(AMPA)-type glutamate receptors (AMPARs) are the predominant excitatory neurotransmitter receptors in the brain, where they mediate synaptic transmission and plasticity. Excessive AMPAR activation leads to diseases such as epilepsy. AMPAR propertie...

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Detalles Bibliográficos
Autores principales:	Dohrke, Jan-Niklas, Watson, Jake F., Birchall, Kristian, Greger, Ingo H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Neurobiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586208/ https://www.ncbi.nlm.nih.gov/pubmed/32747446 http://dx.doi.org/10.1074/jbc.RA120.014135

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