Cargando…

Regulatory effects of post-translational modifications on zDHHC S-acyltransferases

The human zDHHC S-acyltransferase family comprises 23 enzymes that mediate the S-acylation of a multitude of cellular proteins, including channels, receptors, transporters, signaling molecules, scaffolds, and chaperones. This reversible post-transitional modification (PTM) involves the attachment of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zmuda, Filip, Chamberlain, Luke H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	JBC Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586229/ https://www.ncbi.nlm.nih.gov/pubmed/32817054 http://dx.doi.org/10.1074/jbc.REV120.014717

Ejemplares similares

Substrate recruitment by zDHHC protein acyltransferases
por: Malgapo, Martin Ian P., et al.
Publicado: (2021)

In vitro reconstitution of substrate S-acylation by the zDHHC family of protein acyltransferases
por: Elliot Murphy, R., et al.
Publicado: (2022)

Identification of a Novel Sequence Motif Recognized by the Ankyrin Repeat Domain of zDHHC17/13 S-Acyltransferases
por: Lemonidis, Kimon, et al.
Publicado: (2015)

S-acylation of Sprouty and SPRED proteins by the S-acyltransferase zDHHC17 involves a novel mode of enzyme–substrate interaction
por: Butler, Liam, et al.
Publicado: (2022)

Control of protein palmitoylation by regulating substrate recruitment to a zDHHC-protein acyltransferase
por: Plain, Fiona, et al.
Publicado: (2020)

Peptide array-based screening reveals a large number of proteins interacting with the ankyrin-repeat domain of the zDHHC17 S-acyltransferase
por: Lemonidis, Kimon, et al.
Publicado: (2017)

The Golgi S-acylation machinery comprises zDHHC enzymes with major differences in substrate affinity and S-acylation activity
por: Lemonidis, Kimon, et al.
Publicado: (2014)

zDHHC9 and the Control of Natriuretic Peptide Secretion by the Heart
por: Fuller, William
Publicado: (2023)

Regulation of dendrite morphology and excitatory synapse formation by zDHHC15
por: Shah, Bhavin S., et al.
Publicado: (2019)

The C-terminal domain of zDHHC2 contains distinct sorting signals that regulate intracellular localisation in neurons and neuroendocrine cells
por: Salaun, Christine, et al.
Publicado: (2017)

A potential role for protein palmitoylation and zDHHC16 in DNA damage response
por: Cao, Na, et al.
Publicado: (2016)

The endoplasmic reticulum–localized enzyme zDHHC6 mediates S-acylation of short transmembrane constructs from multiple type I and II membrane proteins
por: Salaun, Christine, et al.
Publicado: (2023)

Dynamic but discordant alterations in zDHHC5 expression and palmitoylation of its substrates in cardiac pathologies
por: Main, Alice, et al.
Publicado: (2022)

Antioxidant and Anticancer Functions of Protein Acyltransferase DHHC3
por: Sharma, Chandan, et al.
Publicado: (2022)

Update and nomenclature proposal for mammalian lysophospholipid acyltransferases, which create membrane phospholipid diversity
por: Valentine, William J., et al.
Publicado: (2021)

Putative DHHC-Cysteine-Rich Domain S-Acyltransferase in Plants
por: Yuan, Xiaowei, et al.
Publicado: (2013)

Multiple pro-tumor roles for protein acyltransferase DHHC3
por: Sharma, Chandan, et al.
Publicado: (2017)

Ready, SET, Go: Post-translational regulation of the histone lysine methylation network in budding yeast
por: Separovich, Ryan J., et al.
Publicado: (2021)

Regulation of hippocampal excitatory synapses by the Zdhhc5 palmitoyl acyltransferase
por: Shimell, Jordan J., et al.
Publicado: (2021)

zDHHC9 Regulates Cardiomyocyte Rab3a Activity and Atrial Natriuretic Peptide Secretion Through Palmitoylation of Rab3gap1
por: Essandoh, Kobina, et al.
Publicado: (2023)

Effect of mRNA/tRNA mutations on translation speed: Implications for human diseases
por: Davyt, Marcos, et al.
Publicado: (2023)

Regulation of mitochondrial cargo-selective autophagy by posttranslational modifications
por: Lechado Terradas, Anna, et al.
Publicado: (2021)

Regulation of translation by one-carbon metabolism in bacteria and eukaryotic organelles
por: Shetty, Sunil, et al.
Publicado: (2020)

Targeted protein posttranslational modifications by chemically induced proximity for cancer therapy
por: Peng, Yunhua, et al.
Publicado: (2023)

Palmitoyl acyltransferase DHHC21 mediates endothelial dysfunction in systemic inflammatory response syndrome
por: Beard, Richard S., et al.
Publicado: (2016)

Molecular Dynamics of DHHC20 Acyltransferase Suggests Principles of Lipid and Protein Substrate Selectivity
por: Panina, Irina, et al.
Publicado: (2022)

Unlocking the mysteries of alpha-N-terminal methylation and its diverse regulatory functions
por: Chen, Panyue, et al.
Publicado: (2023)

The detection and functions of RNA modification m(6)A based on m(6)A writers and erasers
por: Zhang, Wei, et al.
Publicado: (2021)

Emerging functional principles of tRNA-derived small RNAs and other regulatory small RNAs
por: Chen, Qi, et al.
Publicado: (2023)

eIF3d: A driver of noncanonical cap–dependent translation of specific mRNAs and a trigger of biological/pathological processes
por: Ma, Shijie, et al.
Publicado: (2023)

Analysis of substrate specificity of human DHHC protein acyltransferases using a yeast expression system
por: Ohno, Yusuke, et al.
Publicado: (2012)

Structure and function of STAC proteins: Calcium channel modulators and critical components of muscle excitation–contraction coupling
por: Rufenach, Britany, et al.
Publicado: (2021)

Protection of eIF2B from inhibitory phosphorylated eIF2: A viral strategy to maintain mRNA translation during the PKR-triggered integrated stress response
por: Ito, Takuhiro, et al.
Publicado: (2023)

The vacuolar DHHC-CRD protein Pfa3p is a protein acyltransferase for Vac8p
por: Smotrys, Jessica E., et al.
Publicado: (2005)

Structural features of the protein kinase domain and targeted binding by small-molecule inhibitors
por: Arter, Chris, et al.
Publicado: (2022)

S-Acylation of Proteins of Coronavirus and Influenza Virus: Conservation of Acylation Sites in Animal Viruses and DHHC Acyltransferases in Their Animal Reservoirs
por: Abdulrahman, Dina A., et al.
Publicado: (2021)

The U1 antisense morpholino oligonucleotide (AMO) disrupts U1 snRNP structure to promote intronic PCPA modification of pre-mRNAs
por: Feng, Qiumin, et al.
Publicado: (2023)

Bioinformatics Analysis of the Prognostic and Biological Significance of ZDHHC-Protein Acyltransferases in Kidney Renal Clear Cell Carcinoma
por: Liu, Zhuang, et al.
Publicado: (2020)

Coupled Control of Distal Axon Integrity and Somal Responses to Axonal Damage by the Palmitoyl Acyltransferase ZDHHC17
por: Niu, Jingwen, et al.
Publicado: (2020)

GCP16 stabilizes the DHHC9 subfamily of protein acyltransferases through a conserved C-terminal cysteine motif
por: Nguyen, Phillip L., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_o59ts9b8r98ghtv1qre5le9vvj