Cargando…
Evolutionary selection of a 19-stranded mitochondrial β-barrel scaffold bears structural and functional significance
Transmembrane β-barrels of eukaryotic outer mitochondrial membranes (OMMs) are major channels of communication between the cytosol and mitochondria and are indispensable for cellular homeostasis. A structurally intriguing exception to all known transmembrane β-barrels is the unique odd-stranded, i.e...
Autores principales: | Srivastava, Shashank Ranjan, Mahalakshmi, Radhakrishnan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586230/ https://www.ncbi.nlm.nih.gov/pubmed/32817169 http://dx.doi.org/10.1074/jbc.RA120.014366 |
Ejemplares similares
-
N-helix and Cysteines Inter-regulate Human Mitochondrial VDAC-2 Function and Biochemistry
por: Maurya, Svetlana Rajkumar, et al.
Publicado: (2015) -
Single-residue physicochemical characteristics kinetically partition membrane protein self-assembly and aggregation
por: Gupta, Ankit, et al.
Publicado: (2020) -
XRCC4 Protein Interactions with XRCC4-like Factor (XLF) Create an Extended Grooved Scaffold for DNA Ligation and Double Strand Break Repair
por: Hammel, Michal, et al.
Publicado: (2011) -
Stacked Sets of Parallel, In-register β-Strands of β(2)-Microglobulin in Amyloid Fibrils Revealed by Site-directed Spin Labeling and Chemical Labeling
por: Ladner, Carol L., et al.
Publicado: (2010) -
Human Mitochondrial Chaperone (mtHSP70) and Cysteine Desulfurase (NFS1) Bind Preferentially to the Disordered Conformation, Whereas Co-chaperone (HSC20) Binds to the Structured Conformation of the Iron-Sulfur Cluster Scaffold Protein (ISCU)
por: Cai, Kai, et al.
Publicado: (2013)