Cargando…

TIM3 expression on tumor cells predicts response to anti-PD-1 therapy for renal cancer

This study aimed to identify novel prognostic biomarker for advanced renal cell carcinoma (RCC) patients treated with anti-PD-1 therapy, using quantitative multi-immunofluorescence (IF) analysis of tumor immunity. Twenty-five consecutive patients who had metastatic or unresectable RCC treated with a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kato, Renpei, Jinnouchi, Noriaki, Tuyukubo, Takashi, Ikarashi, Daiki, Matsuura, Tomohiko, Maekawa, Shigekatsu, Kato, Yoichiro, Kanehira, Mitsugu, Takata, Ryo, Ishida, Kazuyuki, Obara, Wataru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2020
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586238/ https://www.ncbi.nlm.nih.gov/pubmed/33129110 http://dx.doi.org/10.1016/j.tranon.2020.100918

Ejemplares similares

Improvement of three-dimensional motion sickness using a virtual reality simulator for robot-assisted surgery in undergraduate medical students: A prospective observational study
por: Takata, Ryo, et al.
Publicado: (2021)

Analyses of Nivolumab Exposure and Clinical Safety Between 3-mg/kg Dosing and 240-mg Flat Dosing in Asian Patients with Advanced Renal Cell Carcinoma in the Real-World Clinical Setting
por: Kato, Renpei, et al.
Publicado: (2020)

Relationship between miR‐155 expression and clear cell papillary renal cell carcinoma in the dialyzed kidney
por: Shiomi, Ei, et al.
Publicado: (2021)

Metastatic bladder cancer forming a sigmoidorectal fistula after enfortumab vedotin therapy: a case report
por: Tamada, Shinji, et al.
Publicado: (2023)

Rapid progression of recurrent disease in a patient with renal cell carcinoma with vaginal metastasis
por: Hisano, Mizuki, et al.
Publicado: (2020)

A case of male perineal aggressive angiomyxoma with expressions of female hormone receptors
por: Hisano, Mizuki, et al.
Publicado: (2022)

Characteristics of early-onset hematotoxicity of sunitinib in Japanese patients with renal cell carcinoma
por: Kato, Renpei, et al.
Publicado: (2017)

Dysuria therapeutic agents as an independent prognostic factor for the primary recurrence of non-muscle invasive bladder cancer: a propensity score matching study
por: Kato, Yoichiro, et al.
Publicado: (2021)

Appropriate preoperative membranous urethral length predicts recovery of urinary continence after robot-assisted laparoscopic prostatectomy
por: Ikarashi, Daiki, et al.
Publicado: (2018)

Present status and future perspective of peptide‐based vaccine therapy for urological cancer
por: Obara, Wataru, et al.
Publicado: (2018)

Single-stage laparoscopic surgery for bilateral organ tumors using a transumbilical approach with a zigzag incision: a report of two cases
por: Kato, Yoichiro, et al.
Publicado: (2018)

A prospective study to examine the accuracies and efficacies of prediction systems for response to neoadjuvant chemotherapy for muscle invasive bladder cancer
por: Kato, Yoichiro, et al.
Publicado: (2018)

Phase I clinical trial of cell division associated 1 (CDCA1) peptide vaccination for castration resistant prostate cancer
por: Obara, Wataru, et al.
Publicado: (2017)

Effective induction of cytotoxic T cells recognizing an epitope peptide derived from hypoxia-inducible protein 2 (HIG2) in patients with metastatic renal cell carcinoma
por: Obara, Wataru, et al.
Publicado: (2016)

Efficacy of Everolimus for Treating Renal Angiomyolipoma with Inferior Vena Cava Thrombus Associated with Tuberous Sclerosis: A Case Report
por: Ikarashi, Daiki, et al.
Publicado: (2017)

Comprehensive analysis of somatic copy number alterations in clear cell renal cell carcinoma
por: Tsuyukubo, Takashi, et al.
Publicado: (2020)

Complete Pathological Response to Neoadjuvant Pembrolizumab in a Patient With Chemoresistant Upper Urinary Tract Urothelial Carcinoma: A Case Report
por: Ikarashi, Daiki, et al.
Publicado: (2020)

Sporadic breast metastasis derived from renal cell carcinoma: A case report
por: Ikarashi, Daiki, et al.
Publicado: (2017)

Cribriform pattern in prostate tissues: Predictor for intraductal carcinoma of the prostate based on biopsy and radical prostatectomy pathology
por: Shiomi, Ei, et al.
Publicado: (2022)

Analysis of Expression Patterns of MicroRNAs That Are Closely Associated With Renal Carcinogenesis
por: Shiomi, Ei, et al.
Publicado: (2019)

A case of complete response to chemotherapy followed by cystectomy for adult-onset rhabdomyosarcoma of the bladder
por: Ito, Ayato, et al.
Publicado: (2022)

A case of mid‐ureteral stricture with ipsilateral atrophic kidney in a young adult
por: Machida, Arisa, et al.
Publicado: (2023)

Efficacy of combination therapy with pembrolizumab and axitinib for metastatic renal collecting duct cell carcinoma: A report on two cases
por: Tamada, Shinji, et al.
Publicado: (2022)

Recurrent massive myxoid liposarcoma in retroperitoneum 10 years post initial operation
por: Horiuchi, Takamasa, et al.
Publicado: (2019)

Complete response to perioperative treatment using nivolumab for metastatic renal cell carcinoma: A case report
por: Ikarashi, Daiki, et al.
Publicado: (2019)

Advance renal pelvic cancer caused obstructive jaundice: A case report
por: Ikarashi, Daiki, et al.
Publicado: (2022)

Hyperprogressive disease after avelumab maintenance therapy in a patient with advanced ureter cancer: A case report
por: Ogasawara, Keita, et al.
Publicado: (2022)

Concurrence of villous adenoma and non-muscle invasive bladder cancer arising in the bladder: a case report and review of the literature
por: Kato, Yoichiro, et al.
Publicado: (2013)

Expression of Tim‐1 in primary CNS lymphoma
por: Kishimoto, Wataru, et al.
Publicado: (2016)

Targeting Tim-3 in Cancer With Resistance to PD-1/PD-L1 Blockade
por: Tian, Tian, et al.
Publicado: (2021)

Real-world effectiveness of nivolumab plus ipilimumab and second-line therapy in Japanese untreated patients with metastatic renal cell carcinoma: 2-year analysis from a multicenter retrospective clinical study (J-cardinal study)
por: Kojima, Takahiro, et al.
Publicado: (2022)

Elevation of Tim-3 and PD-1 Expression on T Cells Appears Early in HIV Infection, and Differential Tim-3 and PD-1 Expression Patterns Can Be Induced by Common γ-Chain Cytokines
por: Zhang, Zi-Ning, et al.
Publicado: (2015)

Immune Checkpoint Profiling in Humanized Breast Cancer Mice Revealed Cell-Specific LAG-3/PD-1/TIM-3 Co-Expression and Elevated PD-1/TIM-3 Secretion
por: Bruss, Christina, et al.
Publicado: (2023)

Mast cell activation is enhanced by Tim1:Tim4 interaction but not by Tim-1 antibodies
por: Phong, Binh, et al.
Publicado: (2016)

Significance of upfront cytoreductive nephrectomy stratified by IMDC risk for metastatic renal cell carcinoma in targeted therapy era – a multi-institutional retrospective study
por: Kato, Renpei, et al.
Publicado: (2022)

Correction to: Significance of upfront cytoreductive nephrectomy stratified by IMDC risk for metastatic renal cell carcinoma in targeted therapy era – a multi‑institutional retrospective study
por: Kato, Renpei, et al.
Publicado: (2023)

PD-1 and Tim-3 Pathways Regulate CD8(+) T Cells Function in Atherosclerosis
por: Qiu, Ming-Ke, et al.
Publicado: (2015)

PD‐1+ TIM‐3+ T cells in malignant ascites predict prognosis of gastrointestinal cancer
por: Nakano, Michitaka, et al.
Publicado: (2018)

Impact of germline HLA genotypes on clinical outcomes in patients with urothelial cancer treated with pembrolizumab
por: Takahashi, Shuhei, et al.
Publicado: (2022)

Tim Burton /
por: Marcos Arza, Marcos
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_f7078v69kta24emds8329vgf6j