Radiation-induced Bystander Effect (RIBE) alters mitochondrial metabolism using a human rectal cancer ex vivo explant model

Locally advanced rectal cancer is treated with neoadjuvant-chemoradiotherapy, however only 22% of patients achieve a complete response. Resistance mechanisms are poorly understood. Radiation-induced Bystander Effect (RIBE) describes the effect of radiation on neighbouring unirradiated cells. We inve...

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Detalles Bibliográficos
Autores principales: Heeran, Aisling B., Berrigan, Helen P., Buckley, Croí E., Bottu, Heleena Moni, Prendiville, Orla, Buckley, Amy M., Clarke, Niamh, Donlon, Noel E., Nugent, Timothy S., Durand, Michael, Dunne, Cara, Larkin, John O., Mehigan, Brian, McCormick, Paul, Brennan, Lorraine, Lynam-Lennon, Niamh, O'Sullivan, Jacintha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586242/
https://www.ncbi.nlm.nih.gov/pubmed/33129115
http://dx.doi.org/10.1016/j.tranon.2020.100882

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