A Han Chinese Family With Early-Onset Parkinson's Disease Carrying Novel Frameshift Mutation and Compound Heterozygous Mutation of PRKN Appearing Incompatible With MDS Clinical Diagnostic Criteria

Around 15% of patients with Parkinson's disease (PD) have a family history, and 5–10% have confirmed genetic causes. PRKN is the most common gene responsible for early-onset Parkinson's disease (EOPD), while rare variants of PLA2G6 likely raise PD susceptibility in the Chinese population....

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Detalles Bibliográficos
Autores principales: Gao, Chenyu, Huang, Ting, Chen, Rui, Yuan, Zhenhua, Tian, Youyong, Zhang, Yingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586315/
https://www.ncbi.nlm.nih.gov/pubmed/33154736
http://dx.doi.org/10.3389/fneur.2020.582323

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