Cargando…

Evaluation of Anthelminthic Activity of Tropical Taniferous Plant Extracts Against Haemonchus contortus

INTRODUCTION: The present trial aimed to investigate invitro anthelminthic activities of selected tropical tanniferous plant extract on egg hatchability and larval development inhibition of Haemonchus contortus in sheep. In view of that, three tropical tanniferous plants Rhus glutinosa, Syzygium gui...

Descripción completa

Detalles Bibliográficos
Autores principales: Birhan, Mastewal, Gesses, Tilahun, Kenubih, Ambaye, Dejene, Haileyesus, Yayeh, Muluken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586322/
https://www.ncbi.nlm.nih.gov/pubmed/33117660
http://dx.doi.org/10.2147/VMRR.S225717
_version_ 1783599972105584640
author Birhan, Mastewal
Gesses, Tilahun
Kenubih, Ambaye
Dejene, Haileyesus
Yayeh, Muluken
author_facet Birhan, Mastewal
Gesses, Tilahun
Kenubih, Ambaye
Dejene, Haileyesus
Yayeh, Muluken
author_sort Birhan, Mastewal
collection PubMed
description INTRODUCTION: The present trial aimed to investigate invitro anthelminthic activities of selected tropical tanniferous plant extract on egg hatchability and larval development inhibition of Haemonchus contortus in sheep. In view of that, three tropical tanniferous plants Rhus glutinosa, Syzygium guineensa and Albizia gumifera, were selected based on their relative high content of condensed tannins. METHODS: In this study, eggs were collected from artificially infected with H. contortus. Then the egg was directly subjected to invitro assay with these condensed tannin-enriched extracts using egg hatchability assay and inhibition of larval development assay. RESULTS: The result showed that extracts from all three tropical tanniferous plants demonstrated statistically significant (P < 0.05) dosedependent inhibition of both egg hatchability and larval development. According to IC(50) and IC(90) values, the condensed tannin-enriched extracts inhibiting egg hatching and larval development most potently were Rhus glutinosa followed in descending order of activity by Syzygium guineensa and Albizia gumifera. DISCUSSION: The result of this study showed that these condensed tanninenriched extracts were effective in inhibiting egg hatchability as well as larval development. Therefore, condensed tannin might be recommended as one of the options for the control of H. contortus in sheep.
format Online
Article
Text
id pubmed-7586322
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Dove
record_format MEDLINE/PubMed
spelling pubmed-75863222020-10-27 Evaluation of Anthelminthic Activity of Tropical Taniferous Plant Extracts Against Haemonchus contortus Birhan, Mastewal Gesses, Tilahun Kenubih, Ambaye Dejene, Haileyesus Yayeh, Muluken Vet Med (Auckl) Original Research INTRODUCTION: The present trial aimed to investigate invitro anthelminthic activities of selected tropical tanniferous plant extract on egg hatchability and larval development inhibition of Haemonchus contortus in sheep. In view of that, three tropical tanniferous plants Rhus glutinosa, Syzygium guineensa and Albizia gumifera, were selected based on their relative high content of condensed tannins. METHODS: In this study, eggs were collected from artificially infected with H. contortus. Then the egg was directly subjected to invitro assay with these condensed tannin-enriched extracts using egg hatchability assay and inhibition of larval development assay. RESULTS: The result showed that extracts from all three tropical tanniferous plants demonstrated statistically significant (P < 0.05) dosedependent inhibition of both egg hatchability and larval development. According to IC(50) and IC(90) values, the condensed tannin-enriched extracts inhibiting egg hatching and larval development most potently were Rhus glutinosa followed in descending order of activity by Syzygium guineensa and Albizia gumifera. DISCUSSION: The result of this study showed that these condensed tanninenriched extracts were effective in inhibiting egg hatchability as well as larval development. Therefore, condensed tannin might be recommended as one of the options for the control of H. contortus in sheep. Dove 2020-10-20 /pmc/articles/PMC7586322/ /pubmed/33117660 http://dx.doi.org/10.2147/VMRR.S225717 Text en © 2020 Birhan et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Birhan, Mastewal
Gesses, Tilahun
Kenubih, Ambaye
Dejene, Haileyesus
Yayeh, Muluken
Evaluation of Anthelminthic Activity of Tropical Taniferous Plant Extracts Against Haemonchus contortus
title Evaluation of Anthelminthic Activity of Tropical Taniferous Plant Extracts Against Haemonchus contortus
title_full Evaluation of Anthelminthic Activity of Tropical Taniferous Plant Extracts Against Haemonchus contortus
title_fullStr Evaluation of Anthelminthic Activity of Tropical Taniferous Plant Extracts Against Haemonchus contortus
title_full_unstemmed Evaluation of Anthelminthic Activity of Tropical Taniferous Plant Extracts Against Haemonchus contortus
title_short Evaluation of Anthelminthic Activity of Tropical Taniferous Plant Extracts Against Haemonchus contortus
title_sort evaluation of anthelminthic activity of tropical taniferous plant extracts against haemonchus contortus
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586322/
https://www.ncbi.nlm.nih.gov/pubmed/33117660
http://dx.doi.org/10.2147/VMRR.S225717
work_keys_str_mv AT birhanmastewal evaluationofanthelminthicactivityoftropicaltaniferousplantextractsagainsthaemonchuscontortus
AT gessestilahun evaluationofanthelminthicactivityoftropicaltaniferousplantextractsagainsthaemonchuscontortus
AT kenubihambaye evaluationofanthelminthicactivityoftropicaltaniferousplantextractsagainsthaemonchuscontortus
AT dejenehaileyesus evaluationofanthelminthicactivityoftropicaltaniferousplantextractsagainsthaemonchuscontortus
AT yayehmuluken evaluationofanthelminthicactivityoftropicaltaniferousplantextractsagainsthaemonchuscontortus