Self-Adjuvanting Cancer Vaccines from Conjugation-Ready Lipid A Analogues and Synthetic Long Peptides

[Image: see text] Self-adjuvanting vaccines, wherein an antigenic peptide is covalently bound to an immunostimulating agent, have been shown to be promising tools for immunotherapy. Synthetic Toll-like receptor (TLR) ligands are ideal adjuvants for covalent linking to peptides or proteins. We here i...

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Detalles Bibliográficos
Autores principales: Reintjens, Niels R. M., Tondini, Elena, de Jong, Ana R., Meeuwenoord, Nico J., Chiodo, Fabrizio, Peterse, Evert, Overkleeft, Herman S., Filippov, Dmitri V., van der Marel, Gijsbert A., Ossendorp, Ferry, Codée, Jeroen D. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586330/
https://www.ncbi.nlm.nih.gov/pubmed/32960056
http://dx.doi.org/10.1021/acs.jmedchem.0c00851

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