Cargando…

Role of Lifestyle in Neuroplasticity and Neurogenesis in an Aging Brain

Neuroplasticity is the brain's ability to transform its shape, adapt, and develop a new neuronal connection provided with a new stimulus. The stronger the electrical stimulation, the robust is the transformation. Neurogenesis is a complex process when the new neuronal blast cells present in the...

Descripción completa

Detalles Bibliográficos
Autores principales: Maharjan, Reeju, Diaz Bustamante, Liliana, Ghattas, Kyrillos N, Ilyas, Shahbakht, Al-Refai, Reham, Khan, Safeera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586385/
https://www.ncbi.nlm.nih.gov/pubmed/33133809
http://dx.doi.org/10.7759/cureus.10639
_version_ 1783599985401528320
author Maharjan, Reeju
Diaz Bustamante, Liliana
Ghattas, Kyrillos N
Ilyas, Shahbakht
Al-Refai, Reham
Khan, Safeera
author_facet Maharjan, Reeju
Diaz Bustamante, Liliana
Ghattas, Kyrillos N
Ilyas, Shahbakht
Al-Refai, Reham
Khan, Safeera
author_sort Maharjan, Reeju
collection PubMed
description Neuroplasticity is the brain's ability to transform its shape, adapt, and develop a new neuronal connection provided with a new stimulus. The stronger the electrical stimulation, the robust is the transformation. Neurogenesis is a complex process when the new neuronal blast cells present in the dentate gyrus divide in the hippocampus. We collected articles from the past 11 years for review, using the Medical Subject Headings (MeSH) strategy from PubMed. Quality appraisal was done for each research article using various assessment tools. A total of 24 articles were chosen, applying all the mentioned inclusion and exclusion criteria and reviewed. The reviewed studies emphasized that modifiable lifestyle factors such as diet and exercise should be implemented as an intervention in the elderly for healthy aging of the brain, as the world's aging population is going to be increased, leading to the expansion of health care and cost. Multiple studies have publicized the relation of diet and exercise with cognition function in aging people. A diet consisting of curcumin in its food has its anti-oxidative property, which prevents rapid aging of the brain, other diet patterns such as a caloric restriction diet can influence brain plasticity and preclude the decline of memory. Exercise can increase brain-derived growth factor (BDGF), vascular endothelial growth factor (VEGF), synapsin one, and tyrosine kinase activity that can expand the size of the brain, enhance the plasticity and neurogenesis. This review aimed at exploring lifestyle factors that contribute to neuroplasticity and neurogenesis. Thus, providing a new path for clinicians and researchers to map out the future possible significant benefits for optimal brain aging in a healthy fashion.
format Online
Article
Text
id pubmed-7586385
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-75863852020-10-29 Role of Lifestyle in Neuroplasticity and Neurogenesis in an Aging Brain Maharjan, Reeju Diaz Bustamante, Liliana Ghattas, Kyrillos N Ilyas, Shahbakht Al-Refai, Reham Khan, Safeera Cureus Neurology Neuroplasticity is the brain's ability to transform its shape, adapt, and develop a new neuronal connection provided with a new stimulus. The stronger the electrical stimulation, the robust is the transformation. Neurogenesis is a complex process when the new neuronal blast cells present in the dentate gyrus divide in the hippocampus. We collected articles from the past 11 years for review, using the Medical Subject Headings (MeSH) strategy from PubMed. Quality appraisal was done for each research article using various assessment tools. A total of 24 articles were chosen, applying all the mentioned inclusion and exclusion criteria and reviewed. The reviewed studies emphasized that modifiable lifestyle factors such as diet and exercise should be implemented as an intervention in the elderly for healthy aging of the brain, as the world's aging population is going to be increased, leading to the expansion of health care and cost. Multiple studies have publicized the relation of diet and exercise with cognition function in aging people. A diet consisting of curcumin in its food has its anti-oxidative property, which prevents rapid aging of the brain, other diet patterns such as a caloric restriction diet can influence brain plasticity and preclude the decline of memory. Exercise can increase brain-derived growth factor (BDGF), vascular endothelial growth factor (VEGF), synapsin one, and tyrosine kinase activity that can expand the size of the brain, enhance the plasticity and neurogenesis. This review aimed at exploring lifestyle factors that contribute to neuroplasticity and neurogenesis. Thus, providing a new path for clinicians and researchers to map out the future possible significant benefits for optimal brain aging in a healthy fashion. Cureus 2020-09-24 /pmc/articles/PMC7586385/ /pubmed/33133809 http://dx.doi.org/10.7759/cureus.10639 Text en Copyright © 2020, Maharjan et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurology
Maharjan, Reeju
Diaz Bustamante, Liliana
Ghattas, Kyrillos N
Ilyas, Shahbakht
Al-Refai, Reham
Khan, Safeera
Role of Lifestyle in Neuroplasticity and Neurogenesis in an Aging Brain
title Role of Lifestyle in Neuroplasticity and Neurogenesis in an Aging Brain
title_full Role of Lifestyle in Neuroplasticity and Neurogenesis in an Aging Brain
title_fullStr Role of Lifestyle in Neuroplasticity and Neurogenesis in an Aging Brain
title_full_unstemmed Role of Lifestyle in Neuroplasticity and Neurogenesis in an Aging Brain
title_short Role of Lifestyle in Neuroplasticity and Neurogenesis in an Aging Brain
title_sort role of lifestyle in neuroplasticity and neurogenesis in an aging brain
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586385/
https://www.ncbi.nlm.nih.gov/pubmed/33133809
http://dx.doi.org/10.7759/cureus.10639
work_keys_str_mv AT maharjanreeju roleoflifestyleinneuroplasticityandneurogenesisinanagingbrain
AT diazbustamanteliliana roleoflifestyleinneuroplasticityandneurogenesisinanagingbrain
AT ghattaskyrillosn roleoflifestyleinneuroplasticityandneurogenesisinanagingbrain
AT ilyasshahbakht roleoflifestyleinneuroplasticityandneurogenesisinanagingbrain
AT alrefaireham roleoflifestyleinneuroplasticityandneurogenesisinanagingbrain
AT khansafeera roleoflifestyleinneuroplasticityandneurogenesisinanagingbrain