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RNA editing in cancer impacts mRNA abundance in immune response pathways

BACKGROUND: RNA editing generates modifications to the RNA sequences, thereby increasing protein diversity and shaping various layers of gene regulation. Recent studies have revealed global shifts in editing levels across many cancer types, as well as a few specific mechanisms implicating individual...

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Detalles Bibliográficos
Autores principales: Chan, Tracey W., Fu, Ting, Bahn, Jae Hoon, Jun, Hyun-Ik, Lee, Jae-Hyung, Quinones-Valdez, Giovanni, Cheng, Chonghui, Xiao, Xinshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586670/
https://www.ncbi.nlm.nih.gov/pubmed/33106178
http://dx.doi.org/10.1186/s13059-020-02171-4