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Click‐Chemistry (CuAAC) Trimerization of an α(v)β(6) Integrin Targeting Ga‐68‐Peptide: Enhanced Contrast for in‐Vivo PET Imaging of Human Lung Adenocarcinoma Xenografts

α(v)β(6) Integrin is an epithelial transmembrane protein that recognizes latency‐associated peptide (LAP) and primarily activates transforming growth factor beta (TGF‐β). It is overexpressed in carcinomas (most notably, pancreatic) and other conditions associated with α(v)β(6) integrin‐dependent TGF...

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Detalles Bibliográficos
Autores principales: Quigley, Neil Gerard, Tomassi, Stefano, di Leva, Francesco Saverio, Di Maro, Salvatore, Richter, Frauke, Steiger, Katja, Kossatz, Susanne, Marinelli, Luciana, Notni, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586803/
https://www.ncbi.nlm.nih.gov/pubmed/32359011
http://dx.doi.org/10.1002/cbic.202000200

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