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Comparative Evaluation of Two Hyaluronic Acid Gel Products for the Treatment of Interdental Papillary Defects
OBJECTIVES: The aim was to investigate the efficacy of single injections of two different hyaluronic acid products, Flex Barrier and Revident, in reducing the size of black triangles to treat Nordland-Tarnow Class I and II recessions. MATERIALS AND METHODS: Forty adult patients were recruited with a...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
University of Zagreb School of Dental Medicine, and Croatian Dental Society - Croatian Medical Association
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586896/ https://www.ncbi.nlm.nih.gov/pubmed/33132386 http://dx.doi.org/10.15644/asc54/3/1 |
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author | Mandel, Iván Farkasdi, Sándor Varga, Gábor Nagy, Ákos Károly |
author_facet | Mandel, Iván Farkasdi, Sándor Varga, Gábor Nagy, Ákos Károly |
author_sort | Mandel, Iván |
collection | PubMed |
description | OBJECTIVES: The aim was to investigate the efficacy of single injections of two different hyaluronic acid products, Flex Barrier and Revident, in reducing the size of black triangles to treat Nordland-Tarnow Class I and II recessions. MATERIALS AND METHODS: Forty adult patients were recruited with at least two upper and two lower interdental papilla defects in the front region between canine teeth. According to the Nordland-Tarnow classification of papillary defects, both Class I and Class II recessions were included in the investigation. Patients were randomly assigned to experimental groups to receive single injections of two different hyaluronic acid products, either Flex Barrier or Revident. The untreated sites served as controls. Photographs were taken before and immediately after the treatment, and again after one week and one month. To determine the size of the black triangles, Image J software was used. For statistical analysis, a mixed-design ANOVA was applied. RESULTS: Both Flex Barrier and Revident significantly decreased the size of the treated defects immediately after the treatment and also one week later (p<0.001). The beneficial effect of Revident lasted longer than Flex Barrier as it remained significant even after one month in Revident-treated patients, however, not in the Flex Barrier-treated group. Furthermore, Nordland-Tarnow Class I lesions generally showed a greater improvement than Class II lesions. CONCLUSION: In this proof-of-concept, randomized clinical trial we have demonstrated the clinical applicability of both Flex Barrier and Revident, although Revident gave longer-lasting improvements than Flex Barrier. Further trials are needed to optimize multiple-application protocols for treating gingival black triangles. |
format | Online Article Text |
id | pubmed-7586896 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | University of Zagreb School of Dental Medicine, and Croatian Dental Society - Croatian Medical Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-75868962020-10-30 Comparative Evaluation of Two Hyaluronic Acid Gel Products for the Treatment of Interdental Papillary Defects Mandel, Iván Farkasdi, Sándor Varga, Gábor Nagy, Ákos Károly Acta Stomatol Croat Original Scientific Papers OBJECTIVES: The aim was to investigate the efficacy of single injections of two different hyaluronic acid products, Flex Barrier and Revident, in reducing the size of black triangles to treat Nordland-Tarnow Class I and II recessions. MATERIALS AND METHODS: Forty adult patients were recruited with at least two upper and two lower interdental papilla defects in the front region between canine teeth. According to the Nordland-Tarnow classification of papillary defects, both Class I and Class II recessions were included in the investigation. Patients were randomly assigned to experimental groups to receive single injections of two different hyaluronic acid products, either Flex Barrier or Revident. The untreated sites served as controls. Photographs were taken before and immediately after the treatment, and again after one week and one month. To determine the size of the black triangles, Image J software was used. For statistical analysis, a mixed-design ANOVA was applied. RESULTS: Both Flex Barrier and Revident significantly decreased the size of the treated defects immediately after the treatment and also one week later (p<0.001). The beneficial effect of Revident lasted longer than Flex Barrier as it remained significant even after one month in Revident-treated patients, however, not in the Flex Barrier-treated group. Furthermore, Nordland-Tarnow Class I lesions generally showed a greater improvement than Class II lesions. CONCLUSION: In this proof-of-concept, randomized clinical trial we have demonstrated the clinical applicability of both Flex Barrier and Revident, although Revident gave longer-lasting improvements than Flex Barrier. Further trials are needed to optimize multiple-application protocols for treating gingival black triangles. University of Zagreb School of Dental Medicine, and Croatian Dental Society - Croatian Medical Association 2020-09 /pmc/articles/PMC7586896/ /pubmed/33132386 http://dx.doi.org/10.15644/asc54/3/1 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND) 4.0 License. |
spellingShingle | Original Scientific Papers Mandel, Iván Farkasdi, Sándor Varga, Gábor Nagy, Ákos Károly Comparative Evaluation of Two Hyaluronic Acid Gel Products for the Treatment of Interdental Papillary Defects |
title | Comparative Evaluation of Two Hyaluronic Acid Gel Products for the Treatment of Interdental Papillary Defects |
title_full | Comparative Evaluation of Two Hyaluronic Acid Gel Products for the Treatment of Interdental Papillary Defects |
title_fullStr | Comparative Evaluation of Two Hyaluronic Acid Gel Products for the Treatment of Interdental Papillary Defects |
title_full_unstemmed | Comparative Evaluation of Two Hyaluronic Acid Gel Products for the Treatment of Interdental Papillary Defects |
title_short | Comparative Evaluation of Two Hyaluronic Acid Gel Products for the Treatment of Interdental Papillary Defects |
title_sort | comparative evaluation of two hyaluronic acid gel products for the treatment of interdental papillary defects |
topic | Original Scientific Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586896/ https://www.ncbi.nlm.nih.gov/pubmed/33132386 http://dx.doi.org/10.15644/asc54/3/1 |
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