ASCL1 regulates neurodevelopmental transcription factors and cell cycle genes in brain tumors of glioma mouse models

Glioblastomas (GBMs) are incurable brain tumors with a high degree of cellular heterogeneity and genetic mutations. Transcription factors that normally regulate neural progenitors and glial development are aberrantly coexpressed in GBM, conferring cancer stem‐like properties to drive tumor progressi...

Descripción completa

Detalles Bibliográficos
Autores principales: Vue, Tou Yia, Kollipara, Rahul K., Borromeo, Mark D., Smith, Tyler, Mashimo, Tomoyuki, Burns, Dennis K., Bachoo, Robert M., Johnson, Jane E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587013/
https://www.ncbi.nlm.nih.gov/pubmed/32573857
http://dx.doi.org/10.1002/glia.23873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587013/
https://www.ncbi.nlm.nih.gov/pubmed/32573857
http://dx.doi.org/10.1002/glia.23873

Ejemplares similares