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ASCL1 regulates neurodevelopmental transcription factors and cell cycle genes in brain tumors of glioma mouse models
Glioblastomas (GBMs) are incurable brain tumors with a high degree of cellular heterogeneity and genetic mutations. Transcription factors that normally regulate neural progenitors and glial development are aberrantly coexpressed in GBM, conferring cancer stem‐like properties to drive tumor progressi...
Autores principales: | Vue, Tou Yia, Kollipara, Rahul K., Borromeo, Mark D., Smith, Tyler, Mashimo, Tomoyuki, Burns, Dennis K., Bachoo, Robert M., Johnson, Jane E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587013/ https://www.ncbi.nlm.nih.gov/pubmed/32573857 http://dx.doi.org/10.1002/glia.23873 |
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