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Evaluation of the selectivity of G-quadruplex ligands in living cells with a small molecule fluorescent probe
G-quadruplex has been an emerging target for drug design due to its physiologically important roles in oncology. A number of quadruplex-interactive ligands have been developed by synthetic and medicinal chemists over the past decades. However, the great challenge still remains that the method for de...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587023/ https://www.ncbi.nlm.nih.gov/pubmed/33117978 http://dx.doi.org/10.1016/j.acax.2019.100017 |