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Rrp6 Moonlights in an RNA Exosome-Independent Manner to Promote Cell Survival and Gene Expression during Stress
The nuclear RNA exosome is essential for RNA processing and degradation. Here, we show that the exosome nuclear-specific subunit Rrp6p promotes cell survival during heat stress through the cell wall integrity (CWI) pathway, independently of its catalytic activity or association with the core exosome...
Autores principales: | Wang, Charles, Liu, Yanru, DeMario, Samuel M., Mandric, Igor, Gonzalez-Figueroa, Carlos, Chanfreau, Guillaume F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587046/ https://www.ncbi.nlm.nih.gov/pubmed/32521279 http://dx.doi.org/10.1016/j.celrep.2020.107754 |
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