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Short-term Outcomes for Patients and Providers After Elective Tracheostomy in COVID-19–Positive Patients

BACKGROUND: Urgent guidance is needed on the safety for providers of percutaneous tracheostomy in patients diagnosed with COVID-19. The objective of the study was to demonstrate that percutaneous dilational tracheostomy (PDT) with a period of apnea in patients requiring prolonged mechanical ventilat...

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Autores principales: Murphy, Patrick, Holler, Emma, Lindroth, Heidi, Laughlin, Michelle, Simons, Clark J., Streib, Erik W., Boustani, Malaz, Ortiz, Damaris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587136/
https://www.ncbi.nlm.nih.gov/pubmed/33316758
http://dx.doi.org/10.1016/j.jss.2020.10.013
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author Murphy, Patrick
Holler, Emma
Lindroth, Heidi
Laughlin, Michelle
Simons, Clark J.
Streib, Erik W.
Boustani, Malaz
Ortiz, Damaris
author_facet Murphy, Patrick
Holler, Emma
Lindroth, Heidi
Laughlin, Michelle
Simons, Clark J.
Streib, Erik W.
Boustani, Malaz
Ortiz, Damaris
author_sort Murphy, Patrick
collection PubMed
description BACKGROUND: Urgent guidance is needed on the safety for providers of percutaneous tracheostomy in patients diagnosed with COVID-19. The objective of the study was to demonstrate that percutaneous dilational tracheostomy (PDT) with a period of apnea in patients requiring prolonged mechanical ventilation due to COVID-19 is safe and can be performed for the usual indications in the intensive care unit. METHODS: This study involves an observational case series at a single-center medical intensive care unit at a level-1 trauma center in patients diagnosed with COVID-19 who were assessed for tracheostomy. Success of a modified technique included direct visualization of tracheal access by bronchoscopy and a blind dilation and tracheostomy insertion during a period of patient apnea to reduce aerosolization. Secondary outcomes include transmission rate of COVID-19 to providers and patient complications. RESULTS: From April 6th, 2020 to July 21st, 2020, 2030 patients were admitted to the hospital with COVID-19, 615 required intensive care unit care (30.3%), and 254 patients required mechanical ventilation (12.5%). The mortality rate for patients requiring mechanical ventilation was 29%. Eighteen patients were assessed for PDT, and 11 (61%) underwent the procedure. The majority had failed extubation at least once (72.7%), and the median duration of intubation before tracheostomy was 15 d (interquartile range 13-24). The median positive end-expiratory pressure at time of tracheostomy was 10.8. The median partial pressure of oxygen (PaO2)/FiO2 ratio on the day of tracheostomy was 142.8 (interquartile range 104.5-224.4). Two patients had bleeding complications. At 1-week follow-up, eight patients still required ventilator support (73%). At the most recent follow-up, eight patients (73%) have been liberated from the ventilator, one patient (9%) died as a result of respiratory/multiorgan failure, and two were discharged on the ventilator (18%). Average follow-up was 20 d. None of the surgeons performing PDT have symptoms of or have tested positive for COVID-19. CONCLUSIONS: and relevance: PDT for patients with COVID-19 is safe for health care workers and patients despite higher positive end-expiratory pressure requirements and should be performed for the same indications as other causes of respiratory failure.
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spelling pubmed-75871362020-10-27 Short-term Outcomes for Patients and Providers After Elective Tracheostomy in COVID-19–Positive Patients Murphy, Patrick Holler, Emma Lindroth, Heidi Laughlin, Michelle Simons, Clark J. Streib, Erik W. Boustani, Malaz Ortiz, Damaris J Surg Res Shock/Sepsis/Trauma/Critical Care BACKGROUND: Urgent guidance is needed on the safety for providers of percutaneous tracheostomy in patients diagnosed with COVID-19. The objective of the study was to demonstrate that percutaneous dilational tracheostomy (PDT) with a period of apnea in patients requiring prolonged mechanical ventilation due to COVID-19 is safe and can be performed for the usual indications in the intensive care unit. METHODS: This study involves an observational case series at a single-center medical intensive care unit at a level-1 trauma center in patients diagnosed with COVID-19 who were assessed for tracheostomy. Success of a modified technique included direct visualization of tracheal access by bronchoscopy and a blind dilation and tracheostomy insertion during a period of patient apnea to reduce aerosolization. Secondary outcomes include transmission rate of COVID-19 to providers and patient complications. RESULTS: From April 6th, 2020 to July 21st, 2020, 2030 patients were admitted to the hospital with COVID-19, 615 required intensive care unit care (30.3%), and 254 patients required mechanical ventilation (12.5%). The mortality rate for patients requiring mechanical ventilation was 29%. Eighteen patients were assessed for PDT, and 11 (61%) underwent the procedure. The majority had failed extubation at least once (72.7%), and the median duration of intubation before tracheostomy was 15 d (interquartile range 13-24). The median positive end-expiratory pressure at time of tracheostomy was 10.8. The median partial pressure of oxygen (PaO2)/FiO2 ratio on the day of tracheostomy was 142.8 (interquartile range 104.5-224.4). Two patients had bleeding complications. At 1-week follow-up, eight patients still required ventilator support (73%). At the most recent follow-up, eight patients (73%) have been liberated from the ventilator, one patient (9%) died as a result of respiratory/multiorgan failure, and two were discharged on the ventilator (18%). Average follow-up was 20 d. None of the surgeons performing PDT have symptoms of or have tested positive for COVID-19. CONCLUSIONS: and relevance: PDT for patients with COVID-19 is safe for health care workers and patients despite higher positive end-expiratory pressure requirements and should be performed for the same indications as other causes of respiratory failure. Elsevier Inc. 2021-04 2020-10-26 /pmc/articles/PMC7587136/ /pubmed/33316758 http://dx.doi.org/10.1016/j.jss.2020.10.013 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Shock/Sepsis/Trauma/Critical Care
Murphy, Patrick
Holler, Emma
Lindroth, Heidi
Laughlin, Michelle
Simons, Clark J.
Streib, Erik W.
Boustani, Malaz
Ortiz, Damaris
Short-term Outcomes for Patients and Providers After Elective Tracheostomy in COVID-19–Positive Patients
title Short-term Outcomes for Patients and Providers After Elective Tracheostomy in COVID-19–Positive Patients
title_full Short-term Outcomes for Patients and Providers After Elective Tracheostomy in COVID-19–Positive Patients
title_fullStr Short-term Outcomes for Patients and Providers After Elective Tracheostomy in COVID-19–Positive Patients
title_full_unstemmed Short-term Outcomes for Patients and Providers After Elective Tracheostomy in COVID-19–Positive Patients
title_short Short-term Outcomes for Patients and Providers After Elective Tracheostomy in COVID-19–Positive Patients
title_sort short-term outcomes for patients and providers after elective tracheostomy in covid-19–positive patients
topic Shock/Sepsis/Trauma/Critical Care
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587136/
https://www.ncbi.nlm.nih.gov/pubmed/33316758
http://dx.doi.org/10.1016/j.jss.2020.10.013
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