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Small-Molecule Control of Super-Mendelian Inheritance in Gene Drives
Synthetic CRISPR-based gene-drive systems have tremendous potential in public health and agriculture, such as for fighting vector-borne diseases or suppressing crop pest populations. These elements can rapidly spread in a population by breaching the inheritance limit of 50% dictated by Mendel’s law...
Autores principales: | Del Amo, Víctor López, Leger, Brittany S., Cox, Kurt J., Gill, Shubhroz, Bishop, Alena L., Scanlon, Garrett D., Walker, James A., Gantz, Valentino M., Choudhary, Amit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587219/ https://www.ncbi.nlm.nih.gov/pubmed/32610142 http://dx.doi.org/10.1016/j.celrep.2020.107841 |
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