Lewis Acid-Facilitated Radiofluorination of MN3PU: A LRRK2 Radiotracer

Background: Temperature-sensitive radiopharmaceutical precursors require lower reaction temperatures (<100 °C) during nucleophilic radiofluorination in order to avoid compound thermolysis, often resulting in sub-optimal radiochemical yields (RCYs). To facilitate nucleophilic aromatic substitution...

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Detalles Bibliográficos
Autores principales: Malik, Noeen, Bendre, Shreya, Schirrmacher, Ralf, Schaffer, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587332/
https://www.ncbi.nlm.nih.gov/pubmed/33066671
http://dx.doi.org/10.3390/molecules25204710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587332/
https://www.ncbi.nlm.nih.gov/pubmed/33066671
http://dx.doi.org/10.3390/molecules25204710

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