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Lewis Acid-Facilitated Radiofluorination of MN3PU: A LRRK2 Radiotracer
Background: Temperature-sensitive radiopharmaceutical precursors require lower reaction temperatures (<100 °C) during nucleophilic radiofluorination in order to avoid compound thermolysis, often resulting in sub-optimal radiochemical yields (RCYs). To facilitate nucleophilic aromatic substitution...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587332/ https://www.ncbi.nlm.nih.gov/pubmed/33066671 http://dx.doi.org/10.3390/molecules25204710 |