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Determination of Lekethromycin, a Novel Macrolide Lactone, in Rat Plasma by UPLC-MS/MS and Its Application to a Pharmacokinetic Study

Lekethromycin, a new macrolide lactone, exhibits significant antibacterial activity. In this study, a reliable analytical ultrahigh-performance liquid chromatography electrospray ionization quadrupole Orbitrap high-resolution mass spectrometry (UPLC-ESI-Orbitrap-MS) method was established and valida...

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Detalles Bibliográficos
Autores principales:	Xiao, Hongzhi, Sun, Pan, Qiu, Jicheng, Wang, Jianzhong, Yan, Lei, Zhang, Suxia, Cao, Xingyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587338/ https://www.ncbi.nlm.nih.gov/pubmed/33066303 http://dx.doi.org/10.3390/molecules25204676

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